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Fucose
 
 
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Fucose is a hexose
Hexose

In organic chemistry, a hexose is a monosaccharide with six carbon atoms, having the chemical formula C6H12O6. Hexoses are classified by functional group, with aldohexoses having an aldehyde at position 1, and ketohexoses having a ketone at position 2....
 deoxy sugar
Deoxy sugar

Deoxy sugars are sugars that have had a hydroxyl group replaced with a hydrogen.Examples include:* Deoxyribose * Fucose* Rhamnose...
 with the chemical formula
Chemical formula

A chemical formula is a way of expressing information about the atoms that constitute a particular chemical compound, and how the relationship between those atoms changes in chemical reactions....
 C6H12O5. It is found on N-linked glycans on the mammal
Mammal

Mammals are a class of vertebrate animals whose name is derived from their distinctive feature, mammary glands, with which they feed their young....
ian, insect and plant cell
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
 surface, and is the fundamental sub-unit of the fucoidan
Fucoidan

Fucoidan is a sulfated polysaccharide found mainly in various species of brown seaweed such as kombu, limu moui, bladderwrack, wakame, mozuku, and hijiki ....
 polysaccharide
Polysaccharide

Polysaccharides are relatively complex carbohydrates. They are polymers made up of many monosaccharides joined together by glycosidic bonds. They are therefore very large, often branched, macromolecules....
. Alpha1?3 linked core fucose is a suspected carbohydrate
Carbohydrate

Carbohydrates or saccharides are the most abundant of the four major classes of biomolecules. They fill numerous roles in living things, such as the storage and transport of energy and structural components ....
 antigen
Antigen

An antigen is a substance that prompts the generation of antibodies and can cause an immune response. The word originated from the notion that they can stimulate antibody generation....
 for IgE-mediated allergy
Allergy

Allergy is a Disorder of the immune system often also referred to as atopy. Allergic reactions occur to Natural environmental substances known as allergens; these reactions are Acquired disorder, predictable and rapid....
.

Two structural features distinguish fucose from other six-carbon sugars present in mammals: the lack of a hydroxyl
Hydroxyl

Hydroxyl in chemistry stands for a molecule consisting of an oxygen atom and a hydrogen atom connected by a covalent bond. The neutral form is a hydroxyl Radical and the hydroxyl anion is called a hydroxide....
 group on the carbon at the 6-position (C-6) and the L-configuration.






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Encyclopedia


Fucose is a hexose
Hexose

In organic chemistry, a hexose is a monosaccharide with six carbon atoms, having the chemical formula C6H12O6. Hexoses are classified by functional group, with aldohexoses having an aldehyde at position 1, and ketohexoses having a ketone at position 2....
 deoxy sugar
Deoxy sugar

Deoxy sugars are sugars that have had a hydroxyl group replaced with a hydrogen.Examples include:* Deoxyribose * Fucose* Rhamnose...
 with the chemical formula
Chemical formula

A chemical formula is a way of expressing information about the atoms that constitute a particular chemical compound, and how the relationship between those atoms changes in chemical reactions....
 C6H12O5. It is found on N-linked glycans on the mammal
Mammal

Mammals are a class of vertebrate animals whose name is derived from their distinctive feature, mammary glands, with which they feed their young....
ian, insect and plant cell
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
 surface, and is the fundamental sub-unit of the fucoidan
Fucoidan

Fucoidan is a sulfated polysaccharide found mainly in various species of brown seaweed such as kombu, limu moui, bladderwrack, wakame, mozuku, and hijiki ....
 polysaccharide
Polysaccharide

Polysaccharides are relatively complex carbohydrates. They are polymers made up of many monosaccharides joined together by glycosidic bonds. They are therefore very large, often branched, macromolecules....
. Alpha1?3 linked core fucose is a suspected carbohydrate
Carbohydrate

Carbohydrates or saccharides are the most abundant of the four major classes of biomolecules. They fill numerous roles in living things, such as the storage and transport of energy and structural components ....
 antigen
Antigen

An antigen is a substance that prompts the generation of antibodies and can cause an immune response. The word originated from the notion that they can stimulate antibody generation....
 for IgE-mediated allergy
Allergy

Allergy is a Disorder of the immune system often also referred to as atopy. Allergic reactions occur to Natural environmental substances known as allergens; these reactions are Acquired disorder, predictable and rapid....
.

Two structural features distinguish fucose from other six-carbon sugars present in mammals: the lack of a hydroxyl
Hydroxyl

Hydroxyl in chemistry stands for a molecule consisting of an oxygen atom and a hydrogen atom connected by a covalent bond. The neutral form is a hydroxyl Radical and the hydroxyl anion is called a hydroxide....
 group on the carbon at the 6-position (C-6) and the L-configuration. It is equivalent to 6-deoxy-L-galactose
Galactose

Galactose is a type of Carbohydrate which is less sweetness than glucose. It is considered a nutritive sweetener because it has food energy.Galactan is a polymer of the sugar galactose....
.

In the fucose-containing glycan structures, fucosylated glycans, fucose can exist as a terminal modification or serve as an attachment point for adding other sugars. In human N-linked glycans, fucose is most commonly linked a-1,6 to the reducing terminal beta-N-acetlyglucosamine. However, fucose at the non-reducing termini linked a-1,2 to galactose forms the H antigen, the substructure of the A and B blood group antigens.

Fucose is metabolized by an enzyme called alpha-fucosidase
Fucosidase

Fucosidase, alpha-L- 1, tissue, also known as FUCA1, is a human gene.Alpha-Fucosidase is an enzyme that breaks down fucose....
.

See also


  • Fucitol
    Fucitol

    Fucitol, also known as L-fucitol, 6-deoxy-L-galactitol, and -hexane-1,2,3,4,5-pentol, is a sugar alcohol derived from the North Atlantic seaweed Fucus vesiculosus....
  • Fuculose
    Fuculose

    Fuculose or 6-deoxy-tagatose is a ketohexose deoxy sugar....
  • Fucoidan
    Fucoidan

    Fucoidan is a sulfated polysaccharide found mainly in various species of brown seaweed such as kombu, limu moui, bladderwrack, wakame, mozuku, and hijiki ....