Ferdinand-Jean Darier
Encyclopedia
Ferdinand-Jean Darier was a French
physician
, pathologist and dermatologist called the "father of modern dermatology in France".
, Hungary
to French parents, Darier studied with Louis-Antoine Ranvier
(1835–1922) at the Collège de France
.
Darier discovered several diseases, most notably Darier's disease
, a peculiar figurate erythema
, which he identified in 1889 as psorodermose folliculaire végétante. The other diseases were a follicular keratosis
(Darier-White syndrome), acanthosis nigricans
, dermatofibrosarcoma
(Darier-Ferrand disease), erythema annularis
, subcutaneous sarcoidosis
(Darier-Roussy sarcoid), and a sign, Darier's sign
observed in mastocytosis
.
From 1909 to 1922, Darier was head of the clinical department at the Hôpital Saint-Louis
. He was one of the "big five" of the Paris School of Dermatology, along with Ernest Henri Besnier
(1831–1909), Louis-Anne-Jean Brocq
(1856–1928), Raymond Sabouraud
(1864–1938) and Jean Alfred Fournier
(1832–1915).
Darier wrote the dermatology textbook Précis de dermatologie, which was published in 1909 and translated into Spanish, German and English. He was also the editor of the dermatological encyclopedia Nouvelle Pratique Dermatologique, which was published in eight volumes, beginning in 1936.
of the town Longpont-sur-Orge
from 1925 to 1935.
French people
The French are a nation that share a common French culture and speak the French language as a mother tongue. Historically, the French population are descended from peoples of Celtic, Latin and Germanic origin, and are today a mixture of several ethnic groups...
physician
Physician
A physician is a health care provider who practices the profession of medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury and other physical and mental impairments...
, pathologist and dermatologist called the "father of modern dermatology in France".
Medical
Born in BudapestBudapest
Budapest is the capital of Hungary. As the largest city of Hungary, it is the country's principal political, cultural, commercial, industrial, and transportation centre. In 2011, Budapest had 1,733,685 inhabitants, down from its 1989 peak of 2,113,645 due to suburbanization. The Budapest Commuter...
, Hungary
Hungary
Hungary , officially the Republic of Hungary , is a landlocked country in Central Europe. It is situated in the Carpathian Basin and is bordered by Slovakia to the north, Ukraine and Romania to the east, Serbia and Croatia to the south, Slovenia to the southwest and Austria to the west. The...
to French parents, Darier studied with Louis-Antoine Ranvier
Louis-Antoine Ranvier
Louis-Antoine Ranvier was a French physician, pathologist, anatomist and histologist, who discovered nodes of Ranvier, regularly spaced constrictions of the myelin sheath, occurying at varying intervals along the length of a nerve fiber.Ranvier was born and studied medicine at Lyon, graduating in...
(1835–1922) at the Collège de France
Collège de France
The Collège de France is a higher education and research establishment located in Paris, France, in the 5th arrondissement, or Latin Quarter, across the street from the historical campus of La Sorbonne at the intersection of Rue Saint-Jacques and Rue des Écoles...
.
Darier discovered several diseases, most notably Darier's disease
Darier's disease
Darier's disease , also known as Darier disease, Darier–White disease, Dyskeratosis follicularis and Keratosis follicularis, is an autosomal dominant disorder discovered by French dermatologist Ferdinand-Jean Darier. Darier's is characterized by dark crusty patches on the skin, sometimes containing...
, a peculiar figurate erythema
Erythema
Erythema is redness of the skin, caused by hyperemia of the capillaries in the lower layers of the skin. It occurs with any skin injury, infection, or inflammation...
, which he identified in 1889 as psorodermose folliculaire végétante. The other diseases were a follicular keratosis
Keratosis pilaris
Keratosis pilaris is a common, autosomal dominant, genetic follicular condition that is manifested by the appearance of rough bumps on the skin...
(Darier-White syndrome), acanthosis nigricans
Acanthosis nigricans
Acanthosis nigricans is a brown to black, poorly defined, velvety hyperpigmentation of the skin. It is usually found in body folds, such as the posterior and lateral folds of the neck, the axilla, groin, umbilicus, forehead, and other areas.-Causes:...
, dermatofibrosarcoma
Dermatofibrosarcoma protuberans
Dermatofibrosarcoma protuberans is a very rare tumor. It is a rare neoplasm of the dermis layer of the skin, and is classified as a sarcoma. There is only about 1 case per million per year. DFSP is a fibrosarcoma, more precisely a cutaneous soft tissue sarcoma...
(Darier-Ferrand disease), erythema annularis
Erythema annulare centrifugum
Erythema annulare centrifugum is a descriptive term for a skin lesion. The lesions form consists of redness in a ring form that spreads from the center . EAC was first described by Darier in 1916...
, subcutaneous sarcoidosis
Subcutaneous sarcoidosis
Subcutaneous sarcoidosis is a cutaneous condition characterized by numerous 0.5- to 0.3-cm deep-seated nodules on the trunk and extremities....
(Darier-Roussy sarcoid), and a sign, Darier's sign
Darier's sign
Darier's sign is a change observed after stroking the skin of a person with systemic mastocytosis or urticaria pigmentosa.In general, the skin becomes swollen, itchy and red. This is a result of compression of mast cells, which are hyperactive in these diseases. These mast cells release...
observed in mastocytosis
Mastocytosis
Mastocytosis is a group of rare disorders of both children and adults caused by the presence of too many mast cells and CD34+ mast cell precursors in a person's body.- Classification :Mastocytosis can occur in a variety of forms:...
.
From 1909 to 1922, Darier was head of the clinical department at the Hôpital Saint-Louis
Hôpital Saint-Louis
Hôpital Saint-Louis is a hospital in Paris, France. It is part of the Assistance publique - Hôpitaux de Paris hospital system, and it is located at 1 avenue Claude-Vellefaux, in the 10th arrondissement, near the metro station: Goncourt.-External links:*...
. He was one of the "big five" of the Paris School of Dermatology, along with Ernest Henri Besnier
Ernest Henri Besnier
Ernest Henri Besnier was a French dermatologist and medicinal director of the Hôpital Saint-Louis in Paris. He was a native of Honfleur, département Calvados....
(1831–1909), Louis-Anne-Jean Brocq
Louis-Anne-Jean Brocq
Louis-Anne-Jean Brocq was a French dermatologist who was born in Laroque-Timbaut, a village in the department of Lot-et-Garonne. He practiced medicine in Paris at the Hospice la Rochefoucauld, the Hôpital Broca, and from 1906 to 1921, the Hôpital Saint-Louis...
(1856–1928), Raymond Sabouraud
Raymond Sabouraud
Raymond Sabouraud was a French physician born in Nantes. He specialized in dermatology and mycology, and was also an accomplished painter and sculptor....
(1864–1938) and Jean Alfred Fournier
Jean Alfred Fournier
Jean Alfred Fournier was a French dermatologist who specialized in the study of venereal diseases.As a young man he served as an interne at the Hôpital du Midi as an understudy to Philippe Ricord . In 1863 he became médecine des hôpitaux, and from 1867 worked with Augustin Grisolle at the...
(1832–1915).
Darier wrote the dermatology textbook Précis de dermatologie, which was published in 1909 and translated into Spanish, German and English. He was also the editor of the dermatological encyclopedia Nouvelle Pratique Dermatologique, which was published in eight volumes, beginning in 1936.
Political
Besides his medical activities, Darier was the mayorMayor
In many countries, a Mayor is the highest ranking officer in the municipal government of a town or a large urban city....
of the town Longpont-sur-Orge
Longpont-sur-Orge
Longpont-sur-Orge is a commune in the Essonne department in Île-de-France in northern France.Inhabitants of Longpont-sur-Orge are known as Longipontains.Brico Dépôt, a subsidiary of Kingfisher plc, has its head office in Longpont-sur-Orge.-References:...
from 1925 to 1935.
List of works
- De l’artérite syphilitique (1904)
- Précis de dermatologie (1909)
- Nouvelle Pratique Dermatologique (1936)