Keratosis pilaris
Encyclopedia
Keratosis pilaris is a common, autosomal dominant, genetic
Genetics
Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms....

 follicular
Hair follicle
A hair follicle is a skin organ that produces hair. Hair production occurs in phases, including a growth phase , and cessation phase , and a rest phase . Stem cells are principally responsible for the production of hair....

 condition that is manifested by the appearance of rough bumps on the skin. It most often appears on the back and outer sides of the upper arms (though the lower arms can also be affected), and can also occur on the thigh
Thigh
In humans the thigh is the area between the pelvis and the knee. Anatomically, it is part of the lower limb.The single bone in the thigh is called the femur...

s, hands, and tops of leg
Leg
Łęg may refer to the following places in Poland:*A former name for the town of Ełk *Part of the Czyżyny district of Kraków*Łęg, Pleszew County in Greater Poland Voivodeship...

s, flank
Flank
Flank may refer to:* Flank, the side of either a horse or a military unit*Flanking maneuver in military tactics* Flank , the waveform edge formed when a signal goes high or low...

s, buttocks
Buttocks
The buttocks are two rounded portions of the anatomy, located on the posterior of the pelvic region of apes and humans, and many other bipeds or quadrupeds, and comprise a layer of fat superimposed on the gluteus maximus and gluteus medius muscles. Physiologically, the buttocks enable weight to...

, or any body part except glabrous skin (like the palms or soles of feet). Less commonly, lesions appear on the face
Face
The face is a central sense organ complex, for those animals that have one, normally on the ventral surface of the head, and can, depending on the definition in the human case, include the hair, forehead, eyebrow, eyelashes, eyes, nose, ears, cheeks, mouth, lips, philtrum, temple, teeth, skin, and...

, which may be mistaken for acne
Acne
Acne is a general term used for acneiform eruptions. It is usually used as a synonym for acne vulgaris, but may also refer to:*Acne aestivalis*Acne conglobata*Acne cosmetica*Acne fulminans*Acne keloidalis nuchae*Acne mechanica...

. Keratosis pilaris is completely harmless; however the condition can contribute to or exacerbate depression and anxiety.

Classification

Worldwide, KP affects an estimated 40% of the adult population and approximately 50%-80% of all adolescents. It is more common in women than in men.

There are several different types of keratosis pilaris, including keratosis pilaris rubra (red, inflamed bumps which can be on arms, head, legs), keratosis pilaris alba (rough, bumpy skin with no irritation), keratosis pilaris rubra faceii (reddish rash on the cheeks), and related disorders.

While KP resembles goose bumps
Goose bumps
Goose bumps, also called goose flesh, goose pimples, chill bumps, chicken skin, funky spots, Dasler Bumps, chicken bumps or the medical term cutis anserina, are the bumps on a person's skin at the base of body hairs which may involuntarily develop when a person is cold or experiences strong...

, it is characterized by the appearance of small rough bumps on the skin. As a result, many people with keratosis pilaris do not know they have it, and it is often confused with acne
Acne vulgaris
Acne vulgaris is a common human skin disease, characterized by areas of skin with seborrhea , comedones , papules , pustules , Nodules and possibly scarring...

.

Symptoms and signs

Keratosis pilaris occurs when the human body produces excess keratin
Keratin
Keratin refers to a family of fibrous structural proteins. Keratin is the key of structural material making up the outer layer of human skin. It is also the key structural component of hair and nails...

, a natural protein in the skin. The excess keratin, which is cream colored, surrounds and entraps the hair follicles in the pore. This causes the formation of hard plugs (process known as hyperkeratinization
Hyperkeratinization
Hyperkeratinization is a disorder of the cells lining the inside of a hair follicle. It is the normal function of these cells to detach or slough off from the skin lining at normal intervals. The dead cells are then forced out of the follicle...

). Bearing only cosmetic consequence, the condition most often appears as a proliferation of tiny hard bumps that are seldom sore or itchy. Though people with keratosis pilaris experience this condition year-round, it is during the colder months, when moisture levels in the air are lower, that the problem can become exacerbated and the goose bumps
Goose bumps
Goose bumps, also called goose flesh, goose pimples, chill bumps, chicken skin, funky spots, Dasler Bumps, chicken bumps or the medical term cutis anserina, are the bumps on a person's skin at the base of body hairs which may involuntarily develop when a person is cold or experiences strong...

are apt to look and feel more pronounced in color and texture.

Many KP bumps contain an ingrown hair
Ingrown hair
Ingrown hair is a condition where the hair curls back or grows sideways into the skin. The ingrown hair condition is seen primarily among people having curly hair. It may or may not be accompanied by an infection of the hair follicle or "razor bumps" , which vary in size...

that has coiled. This is a result of the keratinized skin's "capping off" the hair follicle, preventing the hair from exiting. The hair grows encapsulated inside the follicle.

External links

The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
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