David Ginty
Encyclopedia
Dr. David D. Ginty is an American neuroscientist
and developmental biologist
.
He graduated from Mount Saint Mary's College
and received his Ph.D. degree in physiology
from East Carolina University
for graduate work with Edward Seidel, on the regulation of polyamine
compounds and their metabolism during cell growth and proliferation. Moving to Boston
, Ginty completed postdoctoral research, first, with John Wagner at the Dana Faber Cancer Institute at Harvard Medical School
, and then with Michael Greenberg at the Children's Hospital Boston
, where he made several seminal contributions to signal transduction
and growth factor
signaling in neurons.
In 1995, he was invited by Solomon Snyder to move to Baltimore
, Maryland
, to become a new faculty member of the Department of Neuroscience
at the Johns Hopkins University School of Medicine. Currently, he is the professor of Neuroscience
and an investigator of the Howard Hughes Medical Institute
. In addition, he oversees the Neuroscience Graduate program of the Johns Hopkins University School of Medicine, and serves on the editorial board of the journal Neuron
.
In the mid-1990s, he received several young investigator awards including a 1995 Klingenstein Award, a 1996 Pew Biomedical Scholar Award, the Basil O'Conner Scholar Award from the March of Dimes. After becoming established, he received a Jacob Javitz Neuroscience Investigator's Award from the National Institutes of Health
. His lab at Johns Hopkins
discovered functions and mechanisms of action of neuronal growth factors and axon guidance cues, and mechanisms of assembly and functional organization of the neural circuits that underlie autonomic functions and the sense of touch.
Neuroscientist
A neuroscientist is an individual who studies the scientific field of neuroscience or any of its related sub-fields...
and developmental biologist
Developmental biology
Developmental biology is the study of the process by which organisms grow and develop. Modern developmental biology studies the genetic control of cell growth, differentiation and "morphogenesis", which is the process that gives rise to tissues, organs and anatomy.- Related fields of study...
.
He graduated from Mount Saint Mary's College
Mount Saint Mary's University
Mount St. Mary's University, also known as The Mount, is a private, liberal arts, Catholic university in the Catoctin Mountains near Emmitsburg, Maryland. It was founded by French émigré Father John DuBois in 1808 and is the oldest independent Catholic college in the United States...
and received his Ph.D. degree in physiology
Physiology
Physiology is the science of the function of living systems. This includes how organisms, organ systems, organs, cells, and bio-molecules carry out the chemical or physical functions that exist in a living system. The highest honor awarded in physiology is the Nobel Prize in Physiology or...
from East Carolina University
East Carolina University
East Carolina University is a public, coeducational, engaged doctoral/research university located in Greenville, North Carolina, United States. Named East Carolina University by statute and commonly known as ECU or East Carolina, the university is the largest institution of higher learning in...
for graduate work with Edward Seidel, on the regulation of polyamine
Polyamine
A polyamine is an organic compound having two or more primary amino groups .This class of compounds includes several synthetic substances that are important feedstocks for the chemical industry, such as ethylene diamine , 1,3-diaminopropane , and hexamethylenediamine...
compounds and their metabolism during cell growth and proliferation. Moving to Boston
Boston
Boston is the capital of and largest city in Massachusetts, and is one of the oldest cities in the United States. The largest city in New England, Boston is regarded as the unofficial "Capital of New England" for its economic and cultural impact on the entire New England region. The city proper had...
, Ginty completed postdoctoral research, first, with John Wagner at the Dana Faber Cancer Institute at Harvard Medical School
Harvard Medical School
Harvard Medical School is the graduate medical school of Harvard University. It is located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts....
, and then with Michael Greenberg at the Children's Hospital Boston
Children's Hospital Boston
Children's Hospital Boston is a 396-licensed bed children's hospital in the Longwood Medical and Academic Area of Boston, Massachusetts.At 300 Longwood Avenue, Children's is adjacent both to its teaching affiliate, Harvard Medical School, and to Dana-Farber Cancer Institute...
, where he made several seminal contributions to signal transduction
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a cell surface receptor. In turn, this receptor alters intracellular molecules creating a response...
and growth factor
Growth factor
A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation and cellular differentiation. Usually it is a protein or a steroid hormone. Growth factors are important for regulating a variety of cellular processes....
signaling in neurons.
In 1995, he was invited by Solomon Snyder to move to Baltimore
Baltimore
Baltimore is the largest independent city in the United States and the largest city and cultural center of the US state of Maryland. The city is located in central Maryland along the tidal portion of the Patapsco River, an arm of the Chesapeake Bay. Baltimore is sometimes referred to as Baltimore...
, Maryland
Maryland
Maryland is a U.S. state located in the Mid Atlantic region of the United States, bordering Virginia, West Virginia, and the District of Columbia to its south and west; Pennsylvania to its north; and Delaware to its east...
, to become a new faculty member of the Department of Neuroscience
Neuroscience
Neuroscience is the scientific study of the nervous system. Traditionally, neuroscience has been seen as a branch of biology. However, it is currently an interdisciplinary science that collaborates with other fields such as chemistry, computer science, engineering, linguistics, mathematics,...
at the Johns Hopkins University School of Medicine. Currently, he is the professor of Neuroscience
Neuroscience
Neuroscience is the scientific study of the nervous system. Traditionally, neuroscience has been seen as a branch of biology. However, it is currently an interdisciplinary science that collaborates with other fields such as chemistry, computer science, engineering, linguistics, mathematics,...
and an investigator of the Howard Hughes Medical Institute
Howard Hughes Medical Institute
Howard Hughes Medical Institute is a United States non-profit medical research organization based in Chevy Chase, Maryland. It was founded by the American businessman Howard Hughes in 1953. It is one of the largest private funding organizations for biological and medical research in the United...
. In addition, he oversees the Neuroscience Graduate program of the Johns Hopkins University School of Medicine, and serves on the editorial board of the journal Neuron
Neuron (journal)
Neuron is a neuroscience scientific journal published by Cell Press. It has been in continuous publication since 1988....
.
In the mid-1990s, he received several young investigator awards including a 1995 Klingenstein Award, a 1996 Pew Biomedical Scholar Award, the Basil O'Conner Scholar Award from the March of Dimes. After becoming established, he received a Jacob Javitz Neuroscience Investigator's Award from the National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...
. His lab at Johns Hopkins
Johns Hopkins
Johns Hopkins was a wealthy American entrepreneur, philanthropist and abolitionist of 19th-century Baltimore, Maryland, now most noted for his philanthropic creation of the institutions that bear his name, namely the Johns Hopkins Hospital, and the Johns Hopkins University and its associated...
discovered functions and mechanisms of action of neuronal growth factors and axon guidance cues, and mechanisms of assembly and functional organization of the neural circuits that underlie autonomic functions and the sense of touch.
External links
- http://neuroscience.jhu.edu/DavidGinty.php Johns Hopkins University Page for the David Ginty Lab
- http://www.hhmi.org/research/investigators/ginty_bio.html David Ginty Investigator Page from HHMI