CankerMelts
Encyclopedia
CankerMelts is a non-prescription over-the-counter medication produced by Orahealth Corporation, located in Bellevue, Washington. CankerMelts are used to treat canker sores (aphthous ulcer) and other trauma-based mouth ailments. The product’s active ingredient is Glycyrrhiza
Glycyrrhiza
Glycyrrhiza is a genus of about 18 accepted species in the legume family , with a subcosmopolitan distribution in Asia, Australia, Europe, and the Americas....

 extract (GX), which comes from the root of the licorice plant. GX is thought to have pain relieving, anti-inflammatory and anti-bacterial properties.

CankerMelts are time-released dissolving discs that adhere in the mouth in order to deliver a GX-collagen
Collagen
Collagen is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content...

 mix directly to the affected area. The disc dissolves in the mouth, slowly releasing the GX and collagen over two to six hours. Research shows that this mix may reduce the healing time of the canker sores from one to two weeks to three to five days.

Testing and Research

The results of a 2006 National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...

 – National Institute of Dental and Craniofacial Research
National Institute of Dental and Craniofacial Research
The National Institute of Dental and Craniofacial Research , is part of the U.S. National Institutes of Health, and as such its function is to the promote the general health of the American people, by improving their oral, dental and craniofacial health. Dr...

 funded study at the University of Washington
University of Washington
University of Washington is a public research university, founded in 1861 in Seattle, Washington, United States. The UW is the largest university in the Northwest and the oldest public university on the West Coast. The university has three campuses, with its largest campus in the University...

showed oral patches with Glycyrrhiza extract were able to decrease ulcer size and significantly lower both passive and stimulated pain in 81 percent of the treatment group.

External links

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