Bakuchiol is a natural phenol and a meroterpene (a chemical compound having a partial terpenoid structure) found in Psoralea corylifolia

Psoralea corylifolia

Psoralea corylifolia is an important plant in the Indian Ayurveda and Tamil Siddha systems of medicine, and also Chinese medicine. The seeds of this plant contain a variety of coumarins including psoralen. The seeds have a variety of medicinal uses, but the specific role of psoralen in these uses...

and in Otholobium pubescens

Otholobium pubescens

Otholobium pubescens is a plant species in the genus Otholobium. It is a peruvian medicinal plant used for the treatment of diabetes and contains bakuchiol....

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One study in rats suggested that bakuchiol and ethanol extracts of the Chinese medicinal plant Psoralea corylifolia could protect against bone loss

Osteoporosis

Osteoporosis is a disease of bones that leads to an increased risk of fracture. In osteoporosis the bone mineral density is reduced, bone microarchitecture is deteriorating, and the amount and variety of proteins in bone is altered...

. Bakuchiol isolated from P. corylifolia has shown activity against numerous Grampositive and Gram-negative oral pathogens. It was able to inhibit the growth of Streptococcus mutans

Streptococcus mutans

Streptococcus mutans is a facultatively aerobic, Gram-positive coccus-shaped bacterium commonly found in the human oral cavity and is a significant contributor to tooth decay.The microbe was first described by J Kilian Clarke in 1924.-Introduction:...

under a range of sucrose

Sucrose

Sucrose is the organic compound commonly known as table sugar and sometimes called saccharose. A white, odorless, crystalline powder with a sweet taste, it is best known for its role in human nutrition. The molecule is a disaccharide composed of glucose and fructose with the molecular formula...

concentrations, pH values and in the presence of organic acids in a temperature-dependent manner and also inhibited the growth of cells adhered to a glass surface.