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Artificial selection

 
Artificial Selection

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Artificial selection



 
 
Artificial selection (or selective breeding
Selective breeding

Selective breeding in domesticated animals is the process of a Breeder developing a cultivated breed over time, and selecting qualities within individuals of the breed that will be best to pass on to the next generation....
) describes intentional breeding for certain traits, or combination of traits. It was defined by Charles Darwin
Charles Darwin

Charles Robert Darwin Royal Society was an English people natural history who realised and presented compelling evidence that all species of life have evolution over time from common descent, through the process he called natural selection....
 in contrast to natural selection
Natural selection

Natural selection is the process by which favorable heritable trait become more common in successive generations of a population of Reproduction organisms, and unfavorable heritable traits become less common, due to differential reproduction of genotypes....
, in which the differential reproduction of organisms with certain traits is attributed to improved survival or reproductive ability (Darwinian fitness").






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Artificial selection (or selective breeding
Selective breeding

Selective breeding in domesticated animals is the process of a Breeder developing a cultivated breed over time, and selecting qualities within individuals of the breed that will be best to pass on to the next generation....
) describes intentional breeding for certain traits, or combination of traits. It was defined by Charles Darwin
Charles Darwin

Charles Robert Darwin Royal Society was an English people natural history who realised and presented compelling evidence that all species of life have evolution over time from common descent, through the process he called natural selection....
 in contrast to natural selection
Natural selection

Natural selection is the process by which favorable heritable trait become more common in successive generations of a population of Reproduction organisms, and unfavorable heritable traits become less common, due to differential reproduction of genotypes....
, in which the differential reproduction of organisms with certain traits is attributed to improved survival or reproductive ability (Darwinian fitness"). Artificial selection can also be unintentional; it is thought that domestication of crops by early humans was largely unintentional.

Historical development

Charles Darwin
Charles Darwin

Charles Robert Darwin Royal Society was an English people natural history who realised and presented compelling evidence that all species of life have evolution over time from common descent, through the process he called natural selection....
  coined the term as an illustration of his proposed wider process of natural selection
Natural selection

Natural selection is the process by which favorable heritable trait become more common in successive generations of a population of Reproduction organisms, and unfavorable heritable traits become less common, due to differential reproduction of genotypes....
. Darwin noted that many domesticated animals and plants had special properties that were developed by intentionally encouraging the breeding potential of individuals who both possessed desirable characteristics, and discouraging the breeding of individuals who had less desirable characteristics.

Darwin used the term once in his work On the Origin of Species:
Slow though the process of selection may be, if feeble man can do much by artificial selection, I can see no limit to the amount of change, to the beauty and complexity of the co adaptations between all organic beings, one with another and with their physical conditions of life, which may have been effected in the long course of time through nature's power of selection, that is by the survival of the fittest
Survival of the fittest

"Survival of the fittest" is a phrase which is shorthand for a concept relating to competition for survival or predominance. Originally applied by Herbert Spencer in his Principles of Biology of 1864, Spencer drew parallels to his ideas of economics with Charles Darwin's theory of evolution by what Darwin termed natural selection....
.


The concept Darwin had with survival of the fittest
Survival of the fittest

"Survival of the fittest" is a phrase which is shorthand for a concept relating to competition for survival or predominance. Originally applied by Herbert Spencer in his Principles of Biology of 1864, Spencer drew parallels to his ideas of economics with Charles Darwin's theory of evolution by what Darwin termed natural selection....
 can't be disassociated from natural selection
Natural selection

Natural selection is the process by which favorable heritable trait become more common in successive generations of a population of Reproduction organisms, and unfavorable heritable traits become less common, due to differential reproduction of genotypes....
 and artificial selection.

Contrast to natural selection

It should be emphasized that there is no real difference in the genetic processes underlying artificial and natural selection, and that the concept of artificial selection was first introduced by Charles Darwin
Charles Darwin

Charles Robert Darwin Royal Society was an English people natural history who realised and presented compelling evidence that all species of life have evolution over time from common descent, through the process he called natural selection....
 as an illustration of the wider process of natural selection
Natural selection

Natural selection is the process by which favorable heritable trait become more common in successive generations of a population of Reproduction organisms, and unfavorable heritable traits become less common, due to differential reproduction of genotypes....
. The selection
Selection

In the context of evolution, certain traits or alleles of a species may be subject to selection depending on the Pragmatics the user has with the word....
 process is termed "artificial" when human preferences or influences have a significant effect on the evolution
Evolution

In biology, evolution is change in the heritability trait of a population of organisms from one generation to the next. These changes are caused by a combination of three main processes: variation, reproduction, and selection....
 of a particular population or species. Indeed, many evolutionary biologists view domestication
Domestication

Domestication or taming refers to the process whereby a population of living things becomes accustomed to a controlled environment by other plants or animals through a process of Selective breeding....
 as a type of natural selection
Natural selection

Natural selection is the process by which favorable heritable trait become more common in successive generations of a population of Reproduction organisms, and unfavorable heritable traits become less common, due to differential reproduction of genotypes....
 and adaptive change that occurs as organisms are brought under the control of human beings.

Laboratory usage

The deliberate exploitation of selective power has become common in experimental biology, particularly in microbiology
Microbiology

Microbiology is the study of microorganisms, which are unicellular or cell-cluster microscopic organisms. This includes eukaryote such as fungi and protists, and prokaryotes, which are bacteria and archaea....
 and genetics
Genetics

Genetics , a discipline of biology, is the science of heredity and Genetic variation in living organisms. The fact that living things inherit traits from their parents has been used since prehistoric times to improve crop plants and animals through selective breeding....
. In a ubiquitous laboratory technique in genetic engineering
Genetic engineering

Engineering There are a number of ways through which genetic engineering is accomplished. Essentially, the process has five main steps# Isolation of the genes of interest...
, gene
Gene

A gene is the basic unit of heredity in a living organism. All living things depend on genes. Genes hold the information to build and maintain their cell and pass genetic trait to offspring....
s are introduced into cells
Cell (biology)

The cell is the structural and functional unit of all known Life organisms. It is the smallest unit of an organism that is classified as living, and is often called the building bricks of life....
 in cell culture
Cell culture

Cell culture is the process by which prokaryote or eukaryote cells are grown under controlled conditions. In practice the term "cell culture" has come to refer to the culturing of cells derived from multicellular eukaryotes, especially animal cells....
, usually bacteria
Bacteria

The Bacteria are a large group of unicellular microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals....
, on a small circular DNA
DNA

Deoxyribonucleic acid is a nucleic acid that contains the genetics instructions used in the development and functioning of all known living organisms and some viruses....
 molecule called a plasmid
Plasmid

File:plasmid .svgA plasmid is an extra-chromosomal DNA molecule separate from the chromosome which is capable of replicating independently of the chromosomal DNA....
 in a process called transfection
Transfection

Transfection is the process of introducing nucleic acids into cells by non-viral methods . The term transformation is preferred to describe non-viral DNA transfer in bacteria and non-animal eukaryotic cells such as fungus, algae and plants....
. The gene of interest is accompanied on the plasmid by a reporter gene
Reporter gene

In molecular biology, a reporter gene is a gene that researchers attach to another gene of interest in cell culture, animals or plants. Certain genes are chosen as reporters because the characteristics they confer on organisms expressing them are easily identified and measured, or because they are selectable markers....
, or "selectable marker", which encodes a specific trait such as antibiotic resistance
Antibiotic resistance

Antibiotic resistance is the ability of a microorganism to withstand the effects of antibiotics. It is a specific type of drug resistance. Antibiotic resistance evolves via natural selection acting upon random mutation, but it can also be engineered by applying an evolutionary stress on a population....
 or ability to grow in high salt concentrations. The cells can then be cultured in an environment that would kill normal cells, but is hospitable to those that have taken up and expressed
Gene expression

Gene expression is the process by which inheritable information from a gene, such as the DNA sequence, is made into a functional gene product, such as protein or RNA....
 the genes on the plasmid. In this way expression of the reporter gene serves as a signal that the gene of interest is also being expressed in the cells.

Another technique used in drug development
Drug development

Drug development or preclinical development is defined in many pharmaceutical companies as the process of taking a new chemical lead through the stages necessary to allow it to be tested in human clinical trials, although a broader definition would encompass the entire process of drug discovery and clinical testing of novel drug candida...
 uses an iterative selective process called in vitro selection
Systematic Evolution of Ligands by Exponential Enrichment

SELEX , also referred to as in vitro selection or in vitro evolution, is a combinatorial technique in molecular biology for producing oligonucleotides of either single-stranded DNA or RNA that specifically bind to a target ligand or ligands....
 to evolve aptamer
Aptamer

Aptamers are oligonucleotide or peptide molecules that bind a specific target molecule. Aptamers are usually created by selecting them from a large random Sequencing pool, but natural aptamers also exist in riboswitches....
s, or nucleic acid
Nucleic acid

A nucleic acid is a macromolecule composed of chains of monomeric nucleotides. In biochemistry these molecules carry genetic information or form structures within Cell ....
 fragments capable of binding specific organic compound
Organic compound

An organic compound is any member of a large class of chemical compounds whose molecules contain carbon. For historical reasons discussed below, a few types of compounds such as carbonates, simple oxides of carbon and cyanides, as well as the allotropes of carbon, are considered Inorganic compound....
s with high binding affinity.

Studies in evolutionary physiology
Evolutionary physiology

Evolutionary physiology is the study of physiological evolution, which is to say, the manner in which the functional characteristics of individuals in a population of organisms have responded to selection across multiple generations during the history of the population....
, behavioral genetics, and other areas of organismal biology have also made use of deliberate artificial selection, though longer generation times and greater difficulty in breeding can make such projects challenging in vertebrates.

See also

  • Animal breeding
    Animal breeding

    Animal breeding is a branch of animal science that addresses the evaluation of the genetic value of domestic livestock. Selecting animals for breeding with superior EBV in growth rate, egg, meat, milk, or wool production, or have other desirable traits has revolutionized agricultural livestock production throughout the world....
  • Experimental evolution
    Experimental evolution

    In evolutionary biology, the field of experimental evolution is concerned with testing hypotheses and evolution by use of controlled experiments....
  • Gene pool
    Gene pool

    In population genetics, a gene pool is the complete set of unique alleles in a species or population....
  • Genetic engineering
    Genetic engineering

    Engineering There are a number of ways through which genetic engineering is accomplished. Essentially, the process has five main steps# Isolation of the genes of interest...
  • Inbreeding
    Inbreeding

    Inbreeding is biological reproduction between close Kinships, whether plant or animal. If practiced repeatedly, it leads to an increase in homozygosity of a population....
  • Marker assisted selection
    Marker assisted selection

    'Marker assisted selection' or 'marker aided selection' is a process whereby a marker is used for indirect selection of a genetic determinant or determinants of a trait of interest ....
  • Plant breeding
    Plant breeding

    Plant breeding is the art and science of changing the genetics of plants for the benefit of humankind. Plant breeding can be accomplished through many different techniques ranging from simply selecting plants with desirable characteristics for propagation, to more complex molecular techniques ....
  • Quantitative genetics
    Quantitative genetics

    Quantitative genetics is the study of continuous traits and its underlying mechanisms. It is effectively an extension of simple Mendelian inheritance in that the combined effect of the many underlying genes results in a Continuous probability distribution of phenotypic values....
  • Selective breeding
    Selective breeding

    Selective breeding in domesticated animals is the process of a Breeder developing a cultivated breed over time, and selecting qualities within individuals of the breed that will be best to pass on to the next generation....
  • Selection methods in plant breeding based on mode of reproduction
    Selection methods in plant breeding based on mode of reproduction

    This article discusses Selection methods in plant breeding based on mode of reproduction. Some plants Reproduction by self-fertilization where pollen from a plant will fertilise reproductive cells or ovules of the same plant....
  • Smart breeding
    Smart breeding

    SMART breeding or Precision breeding refers to an organic farming technique of reproducing a species members together to retain desirable traits and so produce a stronger Hybrid ....