AM-087
Encyclopedia
AM-087 is an analgesic
drug which is a cannabinoid agonist
. It is a derivative of Δ8THC
substituted on the 3-position side chain. AM-087 is a potent CB1 agonist with a Ki
of 0.43nM, making it around 100x more potent than THC
itself. This is most likely due to the bulky bromine
substituent on the side chain.
Analgesic
An analgesic is any member of the group of drugs used to relieve pain . The word analgesic derives from Greek an- and algos ....
drug which is a cannabinoid agonist
Agonist
An agonist is a chemical that binds to a receptor of a cell and triggers a response by that cell. Agonists often mimic the action of a naturally occurring substance...
. It is a derivative of Δ8THC
THC
THC commonly refers to tetrahydrocannabinol, the main active chemical compound in Cannabis.THC may also refer to:* Tan Holdings Corporation...
substituted on the 3-position side chain. AM-087 is a potent CB1 agonist with a Ki
Dissociation constant
In chemistry, biochemistry, and pharmacology, a dissociation constant is a specific type of equilibrium constant that measures the propensity of a larger object to separate reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into...
of 0.43nM, making it around 100x more potent than THC
THC
THC commonly refers to tetrahydrocannabinol, the main active chemical compound in Cannabis.THC may also refer to:* Tan Holdings Corporation...
itself. This is most likely due to the bulky bromine
Bromine
Bromine ") is a chemical element with the symbol Br, an atomic number of 35, and an atomic mass of 79.904. It is in the halogen element group. The element was isolated independently by two chemists, Carl Jacob Löwig and Antoine Jerome Balard, in 1825–1826...
substituent on the side chain.