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Visine

Visine

Overview
Visine is a brand of eye drop
Eye drop
Eye drops are saline-containing drops used as a route to administer medication in the eye. Depending on the condition being treated, they may contain steroids, antihistamines, sympathomimetics, beta receptor blockers, parasympathomimetics, parasympatholytics, prostaglandins, non-steroidal...

s produced by Johnson & Johnson
Johnson & Johnson
Johnson & Johnson is an American multinational pharmaceutical, medical devices and consumer packaged goods manufacturer founded in 1886. Its common stock is a component of the Dow Jones Industrial Average and the company is listed among the Fortune 500....

. Johnson & Johnson acquired Visine, along with Pfizer
Pfizer
Pfizer, Inc. is an American multinational pharmaceutical corporation. The company is based in New York City, New York with its research headquarters in Groton, Connecticut, United States...

's entire consumer healthcare portfolio, in December 2006.

The active ingredients in the original Visine formulation are potassium chloride
Potassium chloride
The chemical compound potassium chloride is a metal halide salt composed of potassium and chlorine. In its pure state, it is odorless and has a white or colorless vitreous crystal appearance, with a crystal structure that cleaves easily in three directions. Potassium chloride crystals are...

 and tetrahydrozoline hydrochloride which is a vasoconstrictor, and therefore constricts the eye
Human eye
The human eye is an organ which reacts to light for several purposes. As a conscious sense organ, the eye allows vision. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth...

's superficial blood vessels to "get the red out", as claimed in Johnson & Johnson's advertising http://www.pfizerch.com/product.aspx?id=330.

Visine is administered topically with 1 to 2 drops applied to the affected eye(s) up to 4 times daily http://www.pfizerch.com/product.aspx?id=330.
  • Those using Visine Original frequently report stinging and burning upon application.

  • Use of this product can cause a rebound effect causing the redness to worsen.
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Encyclopedia
Visine is a brand of eye drop
Eye drop
Eye drops are saline-containing drops used as a route to administer medication in the eye. Depending on the condition being treated, they may contain steroids, antihistamines, sympathomimetics, beta receptor blockers, parasympathomimetics, parasympatholytics, prostaglandins, non-steroidal...

s produced by Johnson & Johnson
Johnson & Johnson
Johnson & Johnson is an American multinational pharmaceutical, medical devices and consumer packaged goods manufacturer founded in 1886. Its common stock is a component of the Dow Jones Industrial Average and the company is listed among the Fortune 500....

. Johnson & Johnson acquired Visine, along with Pfizer
Pfizer
Pfizer, Inc. is an American multinational pharmaceutical corporation. The company is based in New York City, New York with its research headquarters in Groton, Connecticut, United States...

's entire consumer healthcare portfolio, in December 2006.

Visine Original


The active ingredients in the original Visine formulation are potassium chloride
Potassium chloride
The chemical compound potassium chloride is a metal halide salt composed of potassium and chlorine. In its pure state, it is odorless and has a white or colorless vitreous crystal appearance, with a crystal structure that cleaves easily in three directions. Potassium chloride crystals are...

 and tetrahydrozoline hydrochloride which is a vasoconstrictor, and therefore constricts the eye
Human eye
The human eye is an organ which reacts to light for several purposes. As a conscious sense organ, the eye allows vision. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth...

's superficial blood vessels to "get the red out", as claimed in Johnson & Johnson's advertising http://www.pfizerch.com/product.aspx?id=330.

Administration


Visine is administered topically with 1 to 2 drops applied to the affected eye(s) up to 4 times daily http://www.pfizerch.com/product.aspx?id=330.

Adverse effects

  • Those using Visine Original frequently report stinging and burning upon application.

  • Use of this product can cause a rebound effect causing the redness to worsen. Prolonged use can cause blood vessels to be dilated for an extended period of time. Use should be limited unless specified by a doctor.

  • A red eye may often be indicative of more serious underlying ocular condition; simply reducing blood flow to the area won't solve the condition and may even exacerbate symptoms.

  • These drops are also not advised for contact lens wearers because decreased blood flow to the surface of the eye will further lower the levels of oxygen available to the eye.

  • Visine is not to be used by patients with Glaucoma since the production of more liquids only contributes to the problem of high pressure within the eye.

Visine prank myth


A common urban legend
Urban legend
An urban legend, urban myth, urban tale, or contemporary legend, is a form of modern folklore consisting of stories that may or may not have been believed by their tellers to be true...

 is that a few drops of Visine in an unsuspecting victim's drink will cause a harmless bout of diarrhea
Diarrhea
Diarrhea , also spelled diarrhoea, is the condition of having three or more loose or liquid bowel movements per day. It is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause dehydration and...

. This will not produce diarrhea, but oral administration of Visine can induce dangerous side effects related to Visine's ingredient tetrahydrozoline hydrochloride such as:
  • Dangerously low body temperature (hypothermia
    Hypothermia
    Hypothermia is a condition in which core temperature drops below the required temperature for normal metabolism and body functions which is defined as . Body temperature is usually maintained near a constant level of through biologic homeostasis or thermoregulation...

    )
  • Blurred vision
  • Nausea
    Nausea
    Nausea , is a sensation of unease and discomfort in the upper stomach with an involuntary urge to vomit. It often, but not always, precedes vomiting...

     and vomiting
    Vomiting
    Vomiting is the forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose...

  • Difficulty in breathing
    Breathing
    Breathing is the process that moves air in and out of the lungs. Aerobic organisms require oxygen to release energy via respiration, in the form of the metabolism of energy-rich molecules such as glucose. Breathing is only one process that delivers oxygen to where it is needed in the body and...

     or even a complete halt in breathing
  • Elevating (hypertension
    Hypertension
    Hypertension or high blood pressure is a cardiac chronic medical condition in which the systemic arterial blood pressure is elevated. What that means is that the heart is having to work harder than it should to pump the blood around the body. Blood pressure involves two measurements, systolic and...

    ) then dropping (hypotension
    Hypotension
    In physiology and medicine, hypotension is abnormally low blood pressure, especially in the arteries of the systemic circulation. It is best understood as a physiologic state, rather than a disease. It is often associated with shock, though not necessarily indicative of it. Hypotension is the...

    ) blood pressure
  • Possible coma
    Coma
    In medicine, a coma is a state of unconsciousness, lasting more than 6 hours in which a person cannot be awakened, fails to respond normally to painful stimuli, light or sound, lacks a normal sleep-wake cycle and does not initiate voluntary actions. A person in a state of coma is described as...

  • Seizures and tremors


Pfizer
Pfizer
Pfizer, Inc. is an American multinational pharmaceutical corporation. The company is based in New York City, New York with its research headquarters in Groton, Connecticut, United States...

 recommends that anyone ingesting Visine get medical attention or contact a poison control center
Poison control center
A poison control center is a medical facility that is able to provide immediate, free, and expert treatment advice and assistance over the telephone in case of exposure to poisonous or hazardous substances...

 immediately.

Varieties


Currently, Visine is formulated in several varieties:

VISINE A.C. - Astringent/Redness Reliever Eye Drops (Tetrahydrozoline HCl 0.05%, Zinc sulfate
Zinc sulfate
Zinc sulfate is the inorganic compound with the formula ZnSO4 as well as any of three hydrates. It was historically known as "white vitriol". It is a colorless solid that is a common source of soluble zinc ions.-Production and reactivity:...

 0.25%)
  • Special formula for allergens, such as ragweed, dust, or pollen.


VISINE FOR CONTACTS - For Silicone Hydrogel and Hydrophilic lenses
  • Used primarily for comfort during the day, moistening upon awakening and before sleep.


VISINE L.R. (Oxymetazoline
Oxymetazoline
Oxymetazoline is a selective alpha-1 agonist and partial alpha-2 agonist topical decongestant, used in the form of Oxymetazoline hydrochloride, in products such as Afrin, Dristan, Nasivin, Logicin, Vicks Sinex, Visine L.R., Sudafed OM, and Zicam. It was developed from Xylometazoline at E.Merck...

 HCI 0.025%)
  • A longer-lasting formula that lasts for up to 6 hours.


VISINE TEARS (Glycerin 0.2%, Hypromellose
Hypromellose
Hypromellose , short for hydroxypropyl methylcellulose , is a semisynthetic, inert, viscoelastic polymer used as an ophthalmic lubricant, as well as an excipient and controlled-delivery component in oral medicaments, found in a variety of commercial products.As a food additive, hypromellose is an...

 0.2%, Polyethylene glycol
Polyethylene glycol
Polyethylene glycol is a polyether compound with many applications from industrial manufacturing to medicine. It has also been known as polyethylene oxide or polyoxyethylene , depending on its molecular weight, and under the tradename Carbowax.-Available forms:PEG, PEO, or POE refers to an...

 400 1% - Used AS NEEDED)
  • See artificial tears.


VISINE-A (Formerly OCUHIST) (Naphazoline hydrochloride 0.025%, Pheniramine maleate 0.3%)
  • Antihistamine combined with a vasoconstrictor for itchy eyes associated with allergy.

External links