Tombusvirus internal replication element (IRE)
Encyclopedia
In virology
Virology
Virology is the study of viruses and virus-like agents: their structure, classification and evolution, their ways to infect and exploit cells for virus reproduction, the diseases they cause, the techniques to isolate and culture them, and their use in research and therapy...

, the tombusvirus internal replication element (IRE) is a segment of RNA
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....

 located within the region coding for p92 polymerase. This element is essential for viral replication
Viral replication
Viral replication is the term used by virologists to describe the formation of biological viruses during the infection process in the target host cells. Viruses must first get into the cell before viral replication can occur. From the perspective of the virus, the purpose of viral replication is...

; specifically, it is thought to be required at an early stage of replication, such as template recruitment and/or replicase complex assembly.

Other non-coding RNA
Non-coding RNA
A non-coding RNA is a functional RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA , non-messenger RNA and functional RNA . The term small RNA is often used for short bacterial ncRNAs...

 structures in Tombusvirus include the 3' UTR region IV
Tombusvirus 3' UTR region IV
Tombusvirus 3' UTR is an important cis-regulatory region of the Tombus virus genome.Tomato bushy stunt virus is the prototype member of the Tombusviridae family. The genome of this virus is positive sense single stranded RNA. Replication occurs via a negative strand RNA intermediate...

 and 5' UTR
Tombusvirus 5' UTR
Tombusvirus 5' UTR is an important cis-regulatory region of the Tombus virus genome.Tomato bushy stunt virus is the prototype member of the Tombusviridae family. The genome of this virus is positive sense single stranded RNA. Replication occurs via a negative strand RNA intermediate...

.
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