Tombusvirus 3' UTR region IV
Encyclopedia
Tombusvirus 3' UTR is an important cis-regulatory
Cis-regulatory element
A cis-regulatory element or cis-element is a region of DNA or RNA that regulates the expression of genes located on that same molecule of DNA . This term is constructed from the Latin word cis, which means "on the same side as". These cis-regulatory elements are often binding sites for one or...

 region of the Tombus virus
Tombusvirus
The genus Tombusvirus are part of the family Tombusviridae and are members of group IV of the Baltimore classification of viruses. The genomes consist of positive sense single-stranded RNA with a genome size of 4800 nucleotides. The virions are non-enveloped with a diameter of 30 nm and have...

 genome.

Tomato bushy stunt virus is the prototype member of the Tombusviridae family. The genome of this virus is positive sense single stranded RNA. Replication occurs via a negative strand RNA intermediate. In addition to viral proteins p33 and the RNA-dependent RNA polymerase p92, and unknown host factors, conserved and structural regions within the 3'untranslated region (3'UTR) are important for regulating genome replication. This 3' structural element contains a pseudoknot
Pseudoknot
A pseudoknot is a nucleic acid secondary structure containing at least two stem-loop structures in which half of one stem is intercalated between the two halves of another stem. The pseudoknot was first recognized in the turnip yellow mosaic virus in 1982...

.

Other non-coding RNA
Non-coding RNA
A non-coding RNA is a functional RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA , non-messenger RNA and functional RNA . The term small RNA is often used for short bacterial ncRNAs...

 structures in Tombusvirus include the 5' UTR
Tombusvirus 5' UTR
Tombusvirus 5' UTR is an important cis-regulatory region of the Tombus virus genome.Tomato bushy stunt virus is the prototype member of the Tombusviridae family. The genome of this virus is positive sense single stranded RNA. Replication occurs via a negative strand RNA intermediate...

 and an internal replcation element
Tombusvirus internal replication element (IRE)
In virology, the tombusvirus internal replication element is a segment of RNA located within the region coding for p92 polymerase. This element is essential for viral replication; specifically, it is thought to be required at an early stage of replication, such as template recruitment and/or...

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