Temporin
Encyclopedia
Temporins are a family of peptide
Peptide
Peptides are short polymers of amino acid monomers linked by peptide bonds. They are distinguished from proteins on the basis of size, typically containing less than 50 monomer units. The shortest peptides are dipeptides, consisting of two amino acids joined by a single peptide bond...

s isolated originally from the skin secretion of the European red frog Rana temporaria. Peptides belonging to the temporin family have been isolated also from closely related North American frogs.

In elephant
Elephant
Elephants are large land mammals in two extant genera of the family Elephantidae: Elephas and Loxodonta, with the third genus Mammuthus extinct...

s, temporin is secreted by temporal
Temporal bone
The temporal bones are situated at the sides and base of the skull, and lateral to the temporal lobes of the cerebrum.The temporal bone supports that part of the face known as the temple.-Parts:The temporal bone consists of four parts:* Squama temporalis...

 glands
Exocrine gland
Exocrine glands are a type of ductal glands that secrete their products into ducts that lead directly into the external environment...

 during the period of musth
Musth
Musth or must is a periodic condition in bull elephants, characterized by highly aggressive behavior, accompanied by a large rise in reproductive hormones - testosterone levels in an elephant in musth can be as much as 60 times greater than in the same elephant at other times...

. It contains protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

s, lipid
Lipid
Lipids constitute a broad group of naturally occurring molecules that include fats, waxes, sterols, fat-soluble vitamins , monoglycerides, diglycerides, triglycerides, phospholipids, and others...

s (notably cholesterol
Cholesterol
Cholesterol is a complex isoprenoid. Specifically, it is a waxy steroid of fat that is produced in the liver or intestines. It is used to produce hormones and cell membranes and is transported in the blood plasma of all mammals. It is an essential structural component of mammalian cell membranes...

), phenol
Phenol
Phenol, also known as carbolic acid, phenic acid, is an organic compound with the chemical formula C6H5OH. It is a white crystalline solid. The molecule consists of a phenyl , bonded to a hydroxyl group. It is produced on a large scale as a precursor to many materials and useful compounds...

s, cresol
Cresol
Cresols are organic compounds which are methylphenols. They are a widely occurring natural and manufactured group of aromatic organic compounds which are categorized as phenols . Depending on the temperature, cresols can be solid or liquid because they have melting points not far from room...

s and sesquiterpene
Sesquiterpene
Sesquiterpenes are a class of terpenes that consist of three isoprene units and have the molecular formula C15H24. Like monoterpenes, sesquiterpenes may be acyclic or contain rings, including many unique combinations...

s (notably farnesol
Farnesol
Farnesol is a natural organic compound which is an acyclic sesquiterpene alcohol found as a colorless liquid. It is insoluble in water, but miscible with oils...

 and its derivatives).

In old Sanskrit texts, it is referred to as rut
Rut (mammalian reproduction)
The rut is the mating season of ruminant animals such as deer, sheep, elk, moose, caribou, ibex, goats, pronghorn and Asian and African antelope....

fluid (dāna, or mada) and is considered to be a symbol of potency and vigour:
Wild elephants roam the forest and water the trees with their streaming rut fluid. Is it therefore any wonder that the trees in the forest have grown so very tall?


However, even from the point of view of ancient Indian elephant science (gajaśāstra), Temporin (mada) is not a direct symptom of rut.
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