SynBio is a long-term project started in 2011 with the goal of creating innovative medicines, including what are known as Biobetters. This project is a collaborative effort of several Russian and international pharmaceutical companies. The largest private participant of SynBio is the Human Stem Cells Institute (HSCI), a leading Russian biotech company, and the Russian Corporation of Nanotechnologies (RUSNANO) is a key investor. The project is a significant example of international cooperation between researchers in Russia, England, and Germany. Special project company SynBio LLC is headquartered in Moscow.

Currently, SynBio LLC is developing nine drugs based on three biotechnology platforms (Histone

Histone

In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation...

, PolyXen and Gemacell) for the treatment of liver disease

Liver disease

Liver disease is a broad term describing any single number of diseases affecting the liver.-Diseases:* Hepatitis, inflammation of the liver, caused mainly by various viruses but also by some poisons , autoimmunity or hereditary conditions...

, cardiovascular disease

Cardiovascular disease

Heart disease or cardiovascular disease are the class of diseases that involve the heart or blood vessels . While the term technically refers to any disease that affects the cardiovascular system , it is usually used to refer to those related to atherosclerosis...

, acute leukemia

Acute leukemia

Acute leukemia or acute leukaemia is a generic term used to describe a family of serious medical conditions relating to an original diagnosis of leukemia...

, growth hormone deficiency

Growth hormone deficiency

Growth hormone deficiency is a medical condition in which the body does not produce enough growth hormone . Growth hormone, also called somatotropin, is a polypeptide hormone which stimulates growth and cell reproduction...

 and diabetes mellitus

Diabetes mellitus

Diabetes mellitus, often simply referred to as diabetes, is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced...

.

The SynBio project also entails the creation of modern production facilities. These facilities will be dedicated to the manufacturing of the company’s pharmaceutical substances and market-ready medicines once they have successfully undergone clinical testing.

Research and Development Centers

• Xenetic Biosciences (London, Great Britain) is a leading biopharmaceutical company operating from the UK that develops high-value, differentiated pharmaceutical products in the fields of protein drugs, vaccines and anti-cancer drugs.
• SymBioTec GmbH (Saarbrücken, Germany) is a company working to develop next generation medicines for the treatment of cancer and infectious diseases. SymBioTec has a state-of-the-art biotech laboratory equipped for proteomics
  Proteomics
  Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term "proteomics" was first coined in 1997 to make an analogy with...
  
  , cell and molecular biology
  Cell and Molecular Biology
  Cell and Molecular Biology may refer to:* Cell biology* Molecular biology...
  
   as well as biotechnology
  Biotechnology
  Biotechnology is a field of applied biology that involves the use of living organisms and bioprocesses in engineering, technology, medicine and other fields requiring bioproducts. Biotechnology also utilizes these products for manufacturing purpose...
  
  .
• HSCI
  Human Stem Cells Institute
  Human Stem Cells Institute OJSC , Russia’s first public biotech company, was founded in 2003 along with the country’s largest private family cord blood bank, Gemabank. HSCI engages in development, manufacturing and commercialization of cutting-edge products and services in the areas of cell-based,...
  
  (Moscow, Russia) is one of the leading biotech companies of Russia that is engaged in development of cell- and gene-based technologies with promising medical applications.