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Stephen Paget (1855-1926) was an English
England

native_name =|conventional_long_name = England|common_name = England|image_flag = Flag of England.svg|image_coat = England COA.svg|symbol_type = Royal Coat of Arms...
 surgeon
Surgery

Surgery is a medical specialty that uses operative manual and instrumental techniques on a patient to investigate and/or treat a pathological condition such as disease or injury, to help improve bodily function or appearance, or sometimes for some other reason....
, the son of the distinguished surgeon and pathologist
Pathology

Pathology is the study and diagnosis of disease through examination of Organ , tissue , bodily fluids and whole bodies . The term also encompasses the related science study of disease processes, called General pathology....
 Sir James Paget, who has been long credited with proposing the "seed and soil" theory of metastasis
Metastasis

Metastasis , or Metastatic disease, sometimes abbreviated mets, is the spread of a disease from one Organ or part to another non-adjacent organ or part....
, even though in his paper “The Distribution Of Secondary Growths In Cancer Of The Breast”, The Lancet, Volume 133, Issue 3421, 23 March 1889, Pages 571-573, he clearly states “…the chief advocate of this theory of the relation between the embolus and the tissues which receive it is Fuchs…”.






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Stephen Paget (1855-1926) was an English
England

native_name =|conventional_long_name = England|common_name = England|image_flag = Flag of England.svg|image_coat = England COA.svg|symbol_type = Royal Coat of Arms...
 surgeon
Surgery

Surgery is a medical specialty that uses operative manual and instrumental techniques on a patient to investigate and/or treat a pathological condition such as disease or injury, to help improve bodily function or appearance, or sometimes for some other reason....
, the son of the distinguished surgeon and pathologist
Pathology

Pathology is the study and diagnosis of disease through examination of Organ , tissue , bodily fluids and whole bodies . The term also encompasses the related science study of disease processes, called General pathology....
 Sir James Paget, who has been long credited with proposing the "seed and soil" theory of metastasis
Metastasis

Metastasis , or Metastatic disease, sometimes abbreviated mets, is the spread of a disease from one Organ or part to another non-adjacent organ or part....
, even though in his paper “The Distribution Of Secondary Growths In Cancer Of The Breast”, The Lancet, Volume 133, Issue 3421, 23 March 1889, Pages 571-573, he clearly states “…the chief advocate of this theory of the relation between the embolus and the tissues which receive it is Fuchs…”. The paper by Fuchs is “Das Sarkom des Uvealtractus”, Wien, 1882. Graefe's Archiv für Ophthalmologie, XII, 2, p. 233. In his paper, Paget presents and analyzes 735 fatal cases of breast cancer, complete with autopsy, as well as many other cancer cases from the literature and argues that the distribution of metastases cannot be due to chance, concluding that although “the best work in pathology of cancer is done by those who… are studying the nature of the seed…” [the cancer cell], the “observations of the properties of the soil" [the secondary organ] "may also be useful”...