Skp1
Encyclopedia
Skp1 is a small protein
of approximately 160 amino acid
s. As a core component of the SCF-type E3 ubiquitin ligases that mediate protein degradation by the 26S proteosome, Skp1 plays key roles in cell-cycle progression, transcriptional regulation, signal transduction, and many other cellular processes in eukaryotes.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
of approximately 160 amino acid
Amino acid
Amino acids are molecules containing an amine group, a carboxylic acid group and a side-chain that varies between different amino acids. The key elements of an amino acid are carbon, hydrogen, oxygen, and nitrogen...
s. As a core component of the SCF-type E3 ubiquitin ligases that mediate protein degradation by the 26S proteosome, Skp1 plays key roles in cell-cycle progression, transcriptional regulation, signal transduction, and many other cellular processes in eukaryotes.