Seroma
Encyclopedia
A seroma is a pocket of clear serous fluid
Serous fluid
In physiology, the term serous fluid is used for various bodily fluids that are typically pale yellow and transparent, and of a benign nature, that fill the inside of body cavities. Serous fluid originates from serous glands, with secretions enriched with proteins and water. Serous fluid may also...

 that sometimes develops in the body after surgery
Surgery
Surgery is an ancient medical specialty that uses operative manual and instrumental techniques on a patient to investigate and/or treat a pathological condition such as disease or injury, or to help improve bodily function or appearance.An act of performing surgery may be called a surgical...

. When small blood vessels are ruptured, blood plasma
Blood plasma
Blood plasma is the straw-colored liquid component of blood in which the blood cells in whole blood are normally suspended. It makes up about 55% of the total blood volume. It is the intravascular fluid part of extracellular fluid...

 can seep out; inflammation
Inflammation
Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...

 caused by dying injured cells also contributes to the fluid.

Seromas are different from hematoma
Hematoma
A hematoma, or haematoma, is a localized collection of blood outside the blood vessels, usually in liquid form within the tissue. This distinguishes it from an ecchymosis, which is the spread of blood under the skin in a thin layer, commonly called a bruise...

s, which contain red blood cells, and from abscess
Abscess
An abscess is a collection of pus that has accumulated in a cavity formed by the tissue in which the pus resides due to an infectious process or other foreign materials...

es, which contain pus
Pus
Pus is a viscous exudate, typically whitish-yellow, yellow, or yellow-brown, formed at the site of inflammatory during infection. An accumulation of pus in an enclosed tissue space is known as an abscess, whereas a visible collection of pus within or beneath the epidermis is known as a pustule or...

 and result from an infection
Infection
An infection is the colonization of a host organism by parasite species. Infecting parasites seek to use the host's resources to reproduce, often resulting in disease...

.

Seromas can sometimes be caused by a new type of partial-breast radiation therapy, as explained in a recent article in the International Journal of Radiation Oncology, Biology, Physics.

Seromas can also sometimes be caused by injury, such as when the initial swelling from a blow or fall does not fully subside. The remaining serous fluid
Serous fluid
In physiology, the term serous fluid is used for various bodily fluids that are typically pale yellow and transparent, and of a benign nature, that fill the inside of body cavities. Serous fluid originates from serous glands, with secretions enriched with proteins and water. Serous fluid may also...

causes a seroma that the body usually gradually absorbs over time (often taking many days or weeks); however, a knot of calcified tissue sometimes remains.

Seromas are particularly common after mastectomies, abdominal surgeries, and plastic surgery like face lifts. The neck area is usually affected and swells requiring it to be drained. Many patients find that it makes their initial recovery period more difficult, and some need repeated visits to their doctor to have the seroma fluid drained.http://www.twinkletwinkles.com/seroma-after-mastectomy.htm

Treatment

Seromas or lymphatic leaks (lymphoceles) may be difficult to manage at times. Depending on the volume and duration of leakage, control of a leak may take up to a few weeks to resolve with aspiration of serums and the application of pressure dressings.

If a serum or leak does not resolve, for example after a soft tissue biopsy, it may be necessary to take the patient back to the operating room in order to place some form of closed suction drain into the wound. This usually is not necessary and conservative management prevails.
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