Schistosomicide
Encyclopedia
A schistosomicide is a drug used to combat schistosomiasis
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Examples listed in MeSH
include:
Another example is praziquantel
.
Schistosomiasis
Schistosomiasis is a parasitic disease caused by several species of trematodes , a parasitic worm of the genus Schistosoma. Snails often act as an intermediary agent for the infectious diseases until a new human host is found...
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Examples listed in MeSH
Medical Subject Headings
Medical Subject Headings is a comprehensive controlled vocabulary for the purpose of indexing journal articles and books in the life sciences; it can also serve as a thesaurus that facilitates searching...
include:
- amoscanateAmoscanateAmoscanate , also known as nithiocyamine, is an experimental anthelmintic agent of the arylisothiocyanate class which was found to be highly effective in animals against the four major species of schistosomes which infect humans, and is also highly active against hookworm infection. However,...
- arteether
- artemetherArtemetherArtemether is an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It is combined with Lumefantrine and sold by Novartis under the brand names Riamet and Co-Artem.-Chemical nature:...
- chloroxylenolChloroxylenolChloroxylenol is an antimicrobial chemical compound used to control bacteria, algae, and fungi in adhesives, emulsions, paints, and wash tanks. It is also commonly used in antibacterial soaps such as Dettol and ointments, such as the now discontinued Medicated Vaseline. Studies have shown a low...
- hycanthoneHycanthoneHycanthone is a schistosomicide. It is a metabolite of lucanthone....
- lucanthoneLucanthoneLucanthone is a drug used in chemotherapy.Lucanthone is a prodrug and is converted to an active metabolite "hycanthone".-Mechanism of action:...
- meclonazepamMeclonazepamMeclonazepam was discoverd by a team at Hoffmann-Le Roche in the 1970s and is a drug which is a benzodiazepine derivative similar in structure to clonazepam. It has sedative and anxiolytic actions like those of other benzodiazepines, and also has anti-parasitic effects against the parasitic worm...
- niridazoleNiridazoleNiridazole is a schistosomicide. It is used to treat schistosomiasis, the helmintic disease caused by certain flatworms from the genus Schistosoma . It is also known by its trade name Ambilgar. It is usually is given as tablets. Niridazole has central nervous system toxicity and can cause...
- oltiprazOltiprazOltipraz is a schistosomicide.It is also used in tumor prevention....
- oxamniquineOxamniquineOxamniquine is an anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine is a potent single-dose agent for treatment of S...
Another example is praziquantel
Praziquantel
Praziquantel is an anthelmintic effective against flatworms. Praziquantel is not licensed for use in humans in the UK; it is, however, available as a veterinary anthelmintic, and is available for use in humans on a named-patient basis....
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Further reading
- Abdul-Ghani R, Loutfy N, el-Sahn A, Hassan A.Current chemotherapy arsenal for schistosomiasis mansoni: alternatives and challenges. Parasitol Res. 2009 Apr;104(5):955-65. Epub 2009 Mar 3. Review.