Ruedi Aebersold
Encyclopedia
Rudolf Aebersold is a Swiss biologist, regarded as a pioneer in the fields of proteomics
Proteomics
Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term "proteomics" was first coined in 1997 to make an analogy with...
and systems biology
Systems biology
Systems biology is a term used to describe a number of trends in bioscience research, and a movement which draws on those trends. Proponents describe systems biology as a biology-based inter-disciplinary study field that focuses on complex interactions in biological systems, claiming that it uses...
. Prof. Aebersold has primarily researched techniques for measuring proteins in complex samples, in many cases via mass spectrometry
Mass spectrometry
Mass spectrometry is an analytical technique that measures the mass-to-charge ratio of charged particles.It is used for determining masses of particles, for determining the elemental composition of a sample or molecule, and for elucidating the chemical structures of molecules, such as peptides and...
. He is probably best known as one of the inventors of the Isotope-Coded Affinity Tag
Isotope-coded affinity tag
Isotope-coded affinity tags are a gel-free method for quantitative proteomics that relies on chemical labeling reagents. These chemical probes consist of three general elements: a reactive group capable of labeling a defined amino acid side chain , an isotopically coded linker, and a tag for the...
(ICAT) technique for proteomics, a technique for measuring the relative quantities of proteins in one sample relative to another sample by using tags containing stable isotopes of different masses.
Prof. Aebersold is Professor of Systems biology at the Institute of Molecular Systems Biology, Swiss Federal Institute of Technology, Zürich (ETH Zürich). He was one of the founders of the Institute for Systems Biology
Institute for Systems Biology
The Institute for Systems Biology is a non-profit research institution, located in Seattle, Washington, United States. Leroy Hood co-founded the Institute with Alan Aderem and Ruedi Aebersold in 2000....
in Seattle, Washington, and previously had a lab group at this institution.
In recognition of Dr. Aebersold’s outstanding contribution to the field of protein sciences and proteomics the Association of Biomolecular Resource Facilities
Association of Biomolecular Resource Facilities
The Association of Biomolecular Resource Facilities is dedicated to advancing core and research biotechnology laboratories through research, communication, and education...
(ABRF) selected him for the ABRF 2008 Award.