Richard Ulevitch
Encyclopedia
Richard Ulevitch is professor of immunology
and Chairman Emeritus of the Department of Immunology at The Scripps Research Institute
.
Ulevitch has an AB from Washington and Jefferson College and a PhD in Biochemistry from the University of Pennsylvania
. His research attempts to understand the basic mechanisms of the innate immune response to infection. His discoveries, include the definition of the function of receptors in the innate immune system recognizing bacterial products and the discovery of a signal transduction cascade essential for an appropriate innate immune response and for regulating the production of key mediators of inflammation. He is the author of more than 200 scientific articles and his work has been among the most highly cited publications in the field of Immunology.
Ulevitch has been affiliated with multiple advisory panels including the National Institutes of Health
, the American Heart Association
, and the Food and Drug Administration
. He is currently a scientific advisor to Aravis Ventures (Zurich, Switzerland), to 5AM Ventures (Menlo Park, CA) and a consultant to biotechnology and pharmaceutical companies. He was a founding scientific advisor to the Lombard Odier Darier Hentsch Immunology Fund (Geneva, Switzerland). Currently Dr. Ulevitch serves as Chairman of 5AM Venture's Scientific Advisory Board.
Richard is married to Susan, and is the father of David Ulevitch
, the founder and CTO of OpenDNS
.
Immunology
Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders ; the...
and Chairman Emeritus of the Department of Immunology at The Scripps Research Institute
The Scripps Research Institute
The Scripps Research Institute is an American medical research facility that focuses on research in the basic biomedical sciences. Headquartered in La Jolla, California, with a sister facility in Jupiter, Florida, the institute is home to 3,000 scientists, technicians, graduate students, and...
.
Ulevitch has an AB from Washington and Jefferson College and a PhD in Biochemistry from the University of Pennsylvania
University of Pennsylvania
The University of Pennsylvania is a private, Ivy League university located in Philadelphia, Pennsylvania, United States. Penn is the fourth-oldest institution of higher education in the United States,Penn is the fourth-oldest using the founding dates claimed by each institution...
. His research attempts to understand the basic mechanisms of the innate immune response to infection. His discoveries, include the definition of the function of receptors in the innate immune system recognizing bacterial products and the discovery of a signal transduction cascade essential for an appropriate innate immune response and for regulating the production of key mediators of inflammation. He is the author of more than 200 scientific articles and his work has been among the most highly cited publications in the field of Immunology.
Ulevitch has been affiliated with multiple advisory panels including the National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...
, the American Heart Association
American Heart Association
The American Heart Association is a non-profit organization in the United States that fosters appropriate cardiac care in an effort to reduce disability and deaths caused by cardiovascular disease and stroke. It is headquartered in Dallas, Texas...
, and the Food and Drug Administration
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...
. He is currently a scientific advisor to Aravis Ventures (Zurich, Switzerland), to 5AM Ventures (Menlo Park, CA) and a consultant to biotechnology and pharmaceutical companies. He was a founding scientific advisor to the Lombard Odier Darier Hentsch Immunology Fund (Geneva, Switzerland). Currently Dr. Ulevitch serves as Chairman of 5AM Venture's Scientific Advisory Board.
Richard is married to Susan, and is the father of David Ulevitch
David Ulevitch
David A. Ulevitch is founder and current CEO of OpenDNS and founder of EveryDNS.Ulevitch, the youngest child of Susan and Richard Ulevitch, was born and raised in Del Mar, California. Ulevitch's technology career started at an early age when he began working for ElectriCiti, a small regional ISP...
, the founder and CTO of OpenDNS
OpenDNS
OpenDNS is a DNS resolution service. OpenDNS extends DNS adding features such as misspelling correction, phishing protection, and optional content filtering...
.
Selected bibliography
- Aderem, A. and Ulevitch, R.J. Toll-like receptors in the induction of the innate immune response. Nature 406:782-787, 2000.
- Arbibe, L., Mira, J.-P., Kline, L., Godowski, P.J., Ulevitch, R.J. and Knaus, U.G. Tolllike receptor 2-mediated NF-κB activation requires a Rac1-dependent pathway. Nature Immunol. 1:533-540, 2000.
- Werts, C., Tapping, R.I., Mathison, J.C., Chuang, T.-H., Kravchenko, V. V., Saint Girons, I., Haake, D., Godowski, P.J., Hayashi, F., Ozinsky, A.,. Underhill, D., Aderem, A., Tobias, P.S. and Ulevitch, R.J. Leptospiral endotoxin activates cells via a TLR2dependent mechanism. Nature Immunol. 2:346-352, 2001.
- Ge, B., Gram, H., Di Padova, F., Huang, B., New, L., Ulevitch, R., Luo Y., and Han, J. MAP kinase-independent activation of p38a mediated by TAB 1-dependent autophosphorylation of p38a. Science 295:1291-1294, 2002.