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Quadriplegia

 

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Quadriplegia



 
 
Quadriplegia, also known as tetraplegia, is a symptom
Symptom

A symptom is a departure from normal function or feeling which is noticed by a patient, indicating the presence of disease or abnormality. A symptom is subjective, observed by the patient, and not measured....
 in which a human experiences paralysis
Paralysis

Paralysis is the complete loss of muscle function for one or more muscle groups. Paralysis can cause loss of feeling or loss of mobility in the affected area....
 affecting all four limbs, although not necessarily total paralysis or loss of function.

s caused by damage to the brain
Brain

The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as cnidarian and echinoderm have a decentralized nervous system without a brain, while sponges lack any nervous system at all....
 or the spinal cord
Spinal cord

The spinal cord is a long, thin, tubular bundle of neuron and glia that extends from the brain. The brain and spinal cord together make up the central nervous system....
 at a high level - in particular spinal cord injuries secondary to an injury to the cervical spine. The injury, known as a lesion
Lesion

A lesion is any abnormal tissue found on or in an organism, usually damaged by disease or trauma. Lesion is derived from the Latin word laesio which means injury....
, causes victims to lose partial or total mobility of all four limbs, meaning the arms and the legs.

Typical causes of this damage are trauma (such as car crash, gunshot wound, fall, or sports injury) or disease (such as transverse myelitis
Transverse myelitis

Transverse myelitis is a neurological disorder caused by an inflammatory process of the grey matter and white matter matter of the spinal cord, and can cause axonal demyelination....
, polio
Poliomyelitis

Poliomyelitis, often called polio or infantile paralysis, is an acute virus infectious disease spread from person to person, primarily via the fecal-oral route....
, or spina bifida
Spina bifida

Spina bifida is a developmental birth defect involving the neural tube: incomplete closure of the embryonic neural tube results in an incompletely formed spinal cord....
).

It is possible to suffer a broken neck without becoming quadriplegic, such as when the vertebrae are fractured or dislocated but the spinal cord is not damaged.






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Encyclopedia


Quadriplegia, also known as tetraplegia, is a symptom
Symptom

A symptom is a departure from normal function or feeling which is noticed by a patient, indicating the presence of disease or abnormality. A symptom is subjective, observed by the patient, and not measured....
 in which a human experiences paralysis
Paralysis

Paralysis is the complete loss of muscle function for one or more muscle groups. Paralysis can cause loss of feeling or loss of mobility in the affected area....
 affecting all four limbs, although not necessarily total paralysis or loss of function.

Causes

It is caused by damage to the brain
Brain

The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as cnidarian and echinoderm have a decentralized nervous system without a brain, while sponges lack any nervous system at all....
 or the spinal cord
Spinal cord

The spinal cord is a long, thin, tubular bundle of neuron and glia that extends from the brain. The brain and spinal cord together make up the central nervous system....
 at a high level - in particular spinal cord injuries secondary to an injury to the cervical spine. The injury, known as a lesion
Lesion

A lesion is any abnormal tissue found on or in an organism, usually damaged by disease or trauma. Lesion is derived from the Latin word laesio which means injury....
, causes victims to lose partial or total mobility of all four limbs, meaning the arms and the legs.

Typical causes of this damage are trauma (such as car crash, gunshot wound, fall, or sports injury) or disease (such as transverse myelitis
Transverse myelitis

Transverse myelitis is a neurological disorder caused by an inflammatory process of the grey matter and white matter matter of the spinal cord, and can cause axonal demyelination....
, polio
Poliomyelitis

Poliomyelitis, often called polio or infantile paralysis, is an acute virus infectious disease spread from person to person, primarily via the fecal-oral route....
, or spina bifida
Spina bifida

Spina bifida is a developmental birth defect involving the neural tube: incomplete closure of the embryonic neural tube results in an incompletely formed spinal cord....
).

It is possible to suffer a broken neck without becoming quadriplegic, such as when the vertebrae are fractured or dislocated but the spinal cord is not damaged. Conversely, it is possible to injure the spinal cord without breaking the spine, such as when a ruptured disc
Intervertebral disc

Intervertebral discs lie between adjacent vertebra in the vertebral column. Each disc forms a cartilaginous joint to allow slight movement of the vertebrae, and acts as a ligament to hold the vertebrae together....
 or bony spur on the vertebra protrudes into the spinal column.

Symptoms

Although the most obvious symptom is impairment to the limbs, functioning is also impaired in the torso
Torso

Torso is an anatomical term for the central part of the many animal bodies from which extend the neck and limbs. It is sometimes referred to as the trunk....
. This can mean a loss or impairment in controlling bowel
Intestine

In anatomy, the intestine is the segment of the Gastrointestinal tract extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine....
 and bladder
Urinary bladder

In anatomy, the urinary bladder is a solid, muscle, and distensible organ that sits on the pelvic floor in mammals. It is the organ that collects urine excreted by the kidneys prior to disposal by urination....
, sexual function, digestion, breathing, and other autonomic
Autonomic nervous system

The autonomic nervous system is the part of the peripheral nervous system that acts as a control system, maintaining human homeostasis in the body....
 functions. Furthermore, sensation is usually impaired in affected areas. This can manifest as numbness, reduced sensation, or burning neuropathic pain
Neuralgia

Neuralgia or neuropathic pain can be defined most simply as non-nociception pain. Neuralgia is pain produced by a change in neurological structure or function....
.

Secondarily, because of their depressed functioning and immobility, quadriplegics are often more vulnerable to pressure sores
Bedsore

Bedsores, more properly known as pressure ulcers or decubitus ulcers, are lesions caused by many factors such as: unrelieved pressure; friction; humidity; shearing forces; temperature; age; continence and medication; to any part of the body, especially portions over bone or cartilage areas such as sacrum, elbows, knees, ankles etc...
, osteoporosis
Osteoporosis

Osteoporosis is a disease of bone that leads to an increased risk of bone fracture. In osteoporosis the bone mineral density is reduced, bone microarchitecture is disrupted, and the amount and variety of collagen proteins in bone is altered....
 and fractures, frozen joints, spasticity
Spasticity

Spasticity or muscular hypertonicity is a disorder of the central nervous system in which certain muscles continually receive a message to tighten and contract....
, respiratory complications and infections, autonomic dysreflexia
Autonomic dysreflexia

Autonomic dysreflexia,"AD" or "autonomic hyperreflexia" is a condition characterized by a massive sympathetic nervous system discharge that can occur in association with spinal cord injury or disease ....
, deep vein thrombosis
Deep vein thrombosis

In medicine, deep vein thrombosis is the formation of a blood clot in a deep vein. It is a form of thrombophlebitis .Deep vein thrombosis commonly affects the leg veins or the deep veins of the pelvis....
, and cardiovascular disease.

Severity depends on both the level at which the spinal cord is injured and the extent of the injury.

An individual with an injury at C1 (the highest cervical vertebra, at the base of the skull) will likely lose function from the neck down and be ventilator-dependent. An individual with a C7 injury may lose function from the chest down but still retain use of the arms and much of the hands.

The extent of the injury is also important. A complete severing of the spinal cord will result in complete loss of function from that vertebra down. A partial severing or even bruising of the spinal cord results in varying degrees of mixed function and paralysis. For example, there are quadriplegics who have impairment in all four limbs but can still walk and use their hands due to the relatively minor extent of their injury. Others cannot walk but are able to maintain control of bladder, bowel, and sexual function.

It is common to have partial use of some limbs, such as the ability to move the arms but not the hands, or to be able to use the fingers but not have enough grip strength to lift objects. Furthermore, the deficit in the limbs may not be the same on both sides of the body; the left or right side may be more affected, depending on the location of the lesion on the spinal cord.

Terminology

The condition is also termed tetraplegia. Both terms mean "paralysis of four limbs"; tetraplegia is more commonly used in Europe than in the US. In 1991, when the American Spinal Cord Injury Classification system was being revised, it was recommended that the term tetraplegia be used to improve consistency ("tetra", like "plegia", has a Greek root, whereas "quadra" has a Latin root).

However, quadriplegia is still the term more commonly used by the general public in the US. Pentaplegia is a less common term referring to paralysis which also substantially affects head movement.).

Frequency


There are about 5,000 cervical spinal cord injuries per year in the United States and about 1,000 per year in the UK. In 1988, it was estimated that lifetime care of a 27-year-old rendered tetraplegic was about US $1 million and that the total national costs were US $5.6 billion per year.

Prognosis

Delayed diagnosis of cervical spine injury has grave consequences for the victim. About one in twenty cervical fractures are missed, and about two-thirds of these patients have further spinal-cord damage as a result. About 30% of cases of delayed diagnosis of cervical spine injury develop permanent neurological deficits. In high-level cervical injuries, total paralysis from the neck can result. High-level quadriplegics (C5 and above) will likely need constant care and assistance in things such as getting dressed, eating, and bowel and bladder help. Low-level quadriplegics (C6-C7) can often live independently.

Even with "complete" injuries, in some rare cases, through intensive rehabilitation, slight movement can be regained through "rewiring" neural connections
Synaptic plasticity

In neuroscience, synaptic plasticity is the ability of the connection, or synapse, between two neurons to change in Synapse#Synaptic strength. There are several underlying mechanisms that cooperate to achieve synaptic plasticity, including changes in the quantity of neurotransmitters released into a synapse and changes in how effectively cell...
, as in the case of the late actor Christopher Reeve
Christopher Reeve

Christopher D'Olier Reeve was an American actor, film director, film producer, and screenwriter. He established himself early as a The Juilliard School-trained stage actor before portraying Superman in four films, from 1978 to 1987....
.

Related conditions

  • Back-Up Trust
    Back-Up Trust

    The Back-Up Trust is a United Kingdom Charitable organization established for the benefit of people who have been paralysis through spinal cord injury....
  • clearing the cervical spine
    Clearing the cervical spine

    Clearing the cervical spine is the process by which medical professionals determine whether cervical spine injuries exist. This process can take place in the emergency department or take place in the field by appropriately trained emergency medical services personnel....
  • hemiplegia
    Hemiplegia

    Hemiplegia is a condition in which one-half of a patient's body is paralysis. Hemiplegia is more severe than hemiparesis, wherein one half of the body is weakened but not paralysed....
  • paraplegia
    Paraplegia

    Paraplegia is an impairment in motor and/or sensory function of the lower extremities. It is usually the result of spinal cord injury or a congenital condition such as spina bifida which affects the neural elements of the spinal canal....
  • locked-in syndrome
    Locked-In syndrome

    Locked-in syndrome is a condition in which a patient is aware and awake, but cannot move or communicate due to complete paralysis of nearly all voluntary muscles in the body....
  • Brown-Sequard Syndrome
    Brown-Séquard syndrome

    Brown-S?quard syndrome, also known as Brown-S?quard's hemiplegia and Brown-S?quard's paralysis, is a loss of sensation and motor function that is caused by the lateral hemisection of the spinal cord....


See also

  • monkey helper
    Monkey helper

    A monkey helper is a type of assistance animal, similar to an assistance dog, that is specially trained to help quadriplegics, other people with severe spinal cord injuries or mobility-impairments, or vertically challenged individuals....


External links