Pyotr Nikolsky
Encyclopedia
Pyotr Vasilyevich Nikolsky (1858 – 1940) was a Russian dermatologist from Usman
Usman (town)
Usman is a town and the administrative center of Usmansky District of Lipetsk Oblast, Russia, located on the Usman River, south of Lipetsk. Population:...

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He studied medicine at the University of Kiev, and from 1884 was an assistant to Mikhail Stukovenkov at the dermatology clinic in Kiev
Kiev
Kiev or Kyiv is the capital and the largest city of Ukraine, located in the north central part of the country on the Dnieper River. The population as of the 2001 census was 2,611,300. However, higher numbers have been cited in the press....

. In 1900, he became a professor at Warsaw
Warsaw
Warsaw is the capital and largest city of Poland. It is located on the Vistula River, roughly from the Baltic Sea and from the Carpathian Mountains. Its population in 2010 was estimated at 1,716,855 residents with a greater metropolitan area of 2,631,902 residents, making Warsaw the 10th most...

, and later worked as a professor in Rostov
Rostov-on-Don
-History:The mouth of the Don River has been of great commercial and cultural importance since the ancient times. It was the site of the Greek colony Tanais, of the Genoese fort Tana, and of the Turkish fortress Azak...

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He published articles in French as well as Russian on skin diseases and on the treatment of syphilis
Syphilis
Syphilis is a sexually transmitted infection caused by the spirochete bacterium Treponema pallidum subspecies pallidum. The primary route of transmission is through sexual contact; however, it may also be transmitted from mother to fetus during pregnancy or at birth, resulting in congenital syphilis...

. He was the author of L'etat de la dermatologie et de la syphiligraphie en Russie jusqu'à 1884 (The state of dermatology and syphiligraphy in Russia up to 1884).

In 1896, he published an article on pemphigus
Pemphigus
Pemphigus is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes.In pemphigus, autoantibodies form against desmoglein. Desmoglein forms the "glue" that attaches adjacent epidermal cells via attachment points called desmosomes...

, in which he described a dermatological condition involving a weakening relationship among the epidermal layers. This condition is now referred to as "Nikolsky's sign
Nikolsky's sign
Nikolsky's sign is a clinical dermatological sign, named after the Russian physician Pyotr Nikolsky . The sign is positive when slight rubbing of the skin results in exfoliation of the outermost layer....

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