Prokineticin receptor
Encyclopedia
The prokineticin receptor is a G-protein coupled receptor which binds the peptide hormone prokineticin
. There are two variants each encoded by a different gene (PROKR1
, PROKR2
). These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis
.
Prokineticin
Prokineticin is a secreted protein that potently contracts gastrointestinal smooth muscle. Recently, Prokineticins have been recognized in humans and other vertebrates. They are thought to be involved in several important physiological processes like neurogenesis, tissue development, angiogenesis,...
. There are two variants each encoded by a different gene (PROKR1
Prokineticin receptor 1
Prokineticin receptor 1, also known as PKR1, is a human protein encoded by the PROKR1 gene.-Further reading:...
, PROKR2
Prokineticin receptor 2
Prokineticin receptor 2 , in a G-protein coupled receptor encoded by the PROKR2 gene in humans.-External links:* -Further reading:...
). These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis
Angiogenesis
Angiogenesis is the physiological process involving the growth of new blood vessels from pre-existing vessels. Though there has been some debate over terminology, vasculogenesis is the term used for spontaneous blood-vessel formation, and intussusception is the term for the formation of new blood...
.