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Pancreatic juice is a liquid secreted by the pancreas
Pancreas

The pancreas is a gland Organ in the digestive system and endocrine system of vertebrates. It is both an endocrine gland , as well as an exocrine gland, secreting pancreatic juice containing Digestion enzymes that pass to the small intestine....
, which contains a variety of enzymes, including trypsinogen
Trypsinogen

Trypsinogen is the precursor form of the pancreatic enzyme trypsin or a zymogen. It is found in pancreatic juice, along with amylase, lipase, and chymotrypsinogen....
, chymotrypsinogen
Chymotrypsinogen

Chymotrypsinogen is a precursor of the digestive enzyme chymotrypsin .This molecule is inactive and must be cleaved by trypsin, and then by other...
, elastase
Elastase

In molecular biology, elastase is an enzyme from the class of proteases , that break down proteins....
, carboxypeptidase
Carboxypeptidase

Carboxypeptidase is an enzyme that hydrolyzes the carboxy-terminal end of a peptide bond. Humans, animals, and plants contain several types of carboxypeptidases with diverse functions ranging from catabolism to protein maturation....
, pancreatic lipase
Pancreatic lipase

Pancreatic lipase is an enzyme secreted from the pancreas that uses hydrolysis to break apart fat molecules. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which allows the l...
, and amylase
Amylase

Amylase is an enzyme that breaks starch down into sugar. Amylase is present in human saliva, where it begins the chemical process of digestion....
.

Pancreatic juice is alkaline in nature due to the high concentration of bicarbonate ions. This is useful in neutralizing the acidic gastric acid, allowing for effective enzymic action.

Pancreatic juice secretion is regulated by the hormones secretin
Secretin

Secretin is a peptide hormone produced in the S cells of the duodenum in the crypts of Lieberk?hn. Its primary effect is to regulate the pH of the duodenal contents via the control of gastric acid secretion and buffering with bicarbonate....
 and cholecystokinin
Cholecystokinin

Cholecystokinin is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesised by I-cells in the mucosal epithelium of the small intestine and secreted in the duodenum, the first segment of the small intestine, and ca...
, which is produced by the walls of the duodenum
Duodenum

The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms anterior intestine or proximal intestine may be used instead of duodenum....
 upon detection of acid food, proteins and fats.






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Pancreatic juice is a liquid secreted by the pancreas
Pancreas

The pancreas is a gland Organ in the digestive system and endocrine system of vertebrates. It is both an endocrine gland , as well as an exocrine gland, secreting pancreatic juice containing Digestion enzymes that pass to the small intestine....
, which contains a variety of enzymes, including trypsinogen
Trypsinogen

Trypsinogen is the precursor form of the pancreatic enzyme trypsin or a zymogen. It is found in pancreatic juice, along with amylase, lipase, and chymotrypsinogen....
, chymotrypsinogen
Chymotrypsinogen

Chymotrypsinogen is a precursor of the digestive enzyme chymotrypsin .This molecule is inactive and must be cleaved by trypsin, and then by other...
, elastase
Elastase

In molecular biology, elastase is an enzyme from the class of proteases , that break down proteins....
, carboxypeptidase
Carboxypeptidase

Carboxypeptidase is an enzyme that hydrolyzes the carboxy-terminal end of a peptide bond. Humans, animals, and plants contain several types of carboxypeptidases with diverse functions ranging from catabolism to protein maturation....
, pancreatic lipase
Pancreatic lipase

Pancreatic lipase is an enzyme secreted from the pancreas that uses hydrolysis to break apart fat molecules. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which allows the l...
, and amylase
Amylase

Amylase is an enzyme that breaks starch down into sugar. Amylase is present in human saliva, where it begins the chemical process of digestion....
.

Pancreatic juice is alkaline in nature due to the high concentration of bicarbonate ions. This is useful in neutralizing the acidic gastric acid, allowing for effective enzymic action.

Pancreatic juice secretion is regulated by the hormones secretin
Secretin

Secretin is a peptide hormone produced in the S cells of the duodenum in the crypts of Lieberk?hn. Its primary effect is to regulate the pH of the duodenal contents via the control of gastric acid secretion and buffering with bicarbonate....
 and cholecystokinin
Cholecystokinin

Cholecystokinin is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesised by I-cells in the mucosal epithelium of the small intestine and secreted in the duodenum, the first segment of the small intestine, and ca...
, which is produced by the walls of the duodenum
Duodenum

The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms anterior intestine or proximal intestine may be used instead of duodenum....
 upon detection of acid food, proteins and fats. Pancreatic secretion consists of an aqueous bicarbonate component from the duct cells and enzymatic component from the acinar cells.

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