Pachyderma
Encyclopedia
Pachyderma is the thickening of skin
Skin
-Dermis:The dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. The dermis is tightly connected to the epidermis by a basement membrane. It also harbors many Mechanoreceptors that provide the sense of touch and heat...

 like that of a pachyderm
Pachydermata
Pachydermata is an obsolete order of mammals described by Gottlieb Storr, Georges Cuvier and others, at one time recognized by many systematists...

. It occurs in the condition Pachydermoperiostosis
Pachydermoperiostosis
Pachydermoperiostosis or Primary hypertrophic osteoathropathy is a rare genetic disorder that affects both bones and skin. Other names are idiopathic hypertrophic osteoarthropathy or Touraine-Solente-Gole syndrome...

; an X-linked genetic disorder
Genetic disorder
A genetic disorder is an illness caused by abnormalities in genes or chromosomes, especially a condition that is present from before birth. Most genetic disorders are quite rare and affect one person in every several thousands or millions....

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