PPP1R3C
Encyclopedia
Protein phosphatase 1 regulatory subunit 3C also known as PTG is an enzyme
that in humans is encoded by the PPP1R3C gene
.
) participates in the regulation of a wide variety of cellular functions by reversible protein phosphorylation. The ability of PP1 to regulate diverse functions resides in its capacity to interact with a variety of regulatory subunits that may target PP1 to specific subcellular locations, modulate its substrate specificity, and allow its activity to be responsive to extracellular signals. Several targeting subunits of PP1 have been identified, including PPP1R5, the glycogen-binding subunits GM
, GL, PTG
and R6 and PPP1R4, and the nuclear inhibitor of PP1 (PPP1R8
).
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the PPP1R3C gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Function
Protein phosphatase-1 (PP1Protein phosphatase 1
Phosphoprotein phosphatase 1 belongs to a certain class of phosphatases known as protein serine/ threonine phosphatases. This type of phosphatase includes metal-dependent protein phosphatases and aspartate-based phosphatases...
) participates in the regulation of a wide variety of cellular functions by reversible protein phosphorylation. The ability of PP1 to regulate diverse functions resides in its capacity to interact with a variety of regulatory subunits that may target PP1 to specific subcellular locations, modulate its substrate specificity, and allow its activity to be responsive to extracellular signals. Several targeting subunits of PP1 have been identified, including PPP1R5, the glycogen-binding subunits GM
PPP1R3A
Protein phosphatase 1 regulatory subunit 3A is an enzyme that in humans is encoded by the PPP1R3A gene.-Further reading:...
, GL, PTG
PPP1R3C
Protein phosphatase 1 regulatory subunit 3C also known as PTG is an enzyme that in humans is encoded by the PPP1R3C gene.- Function :...
and R6 and PPP1R4, and the nuclear inhibitor of PP1 (PPP1R8
PPP1R8
Nuclear inhibitor of protein phosphatase 1 is an enzyme that in humans is encoded by the PPP1R8 gene.-Interactions:PPP1R8 has been shown to interact with PPP1CA, Histone deacetylase 2, SF3B1 and EED.-Further reading:...
).