PNU-120,596
Encyclopedia
PNU-120,596 is a drug that acts as a potent and selective positive allosteric modulator for the α7
Alpha-7 nicotinic receptor
The alpha-7 nicotinic receptor, also known as the α7 receptor, is a type of nicotinic acetylcholine receptor, consisting entirely of α7 subunits....

 subtype of neural nicotinic acetylcholine receptor
Nicotinic acetylcholine receptor
Nicotinic acetylcholine receptors, or nAChRs, are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons and on the postsynaptic side of the neuromuscular junction...

s. It is used in scientific research into cholinergic regulation of dopamine and glutamate release in the brain.
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