Organomics
Encyclopedia
Organomics is the development and study of organ
Organ (anatomy)
In biology, an organ is a collection of tissues joined in structural unit to serve a common function. Usually there is a main tissue and sporadic tissues . The main tissue is the one that is unique for the specific organ. For example, main tissue in the heart is the myocardium, while sporadic are...

 models and interconnected organ systems in order to better understand tissue
Tissue (biology)
Tissue is a cellular organizational level intermediate between cells and a complete organism. A tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function. These are called tissues because of their identical functioning...

 crosstalk
Crosstalk (biology)
Biological crosstalk refers to instances in which one or more components of a signal transduction pathway affect a different pathway. This can be achieved through a number of ways with the most common form being crosstalk between proteins of signaling cascades. In these signal transduction...

 and how this crosstalk is used to orchestrate systemic physiology
Physiology
Physiology is the science of the function of living systems. This includes how organisms, organ systems, organs, cells, and bio-molecules carry out the chemical or physical functions that exist in a living system. The highest honor awarded in physiology is the Nobel Prize in Physiology or...

. Organome network maps can then be constructed to clarify the interaction between different organs. A task which would be of overwhelming complexity to accomplish in-vivo can thus be broken down into more manageable elements using interconnected in-vitro models.
The models can be constructed using modular cell culture chambers.

See also

  • Omics
  • Tissue Engineering
    Tissue engineering
    Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physio-chemical factors to improve or replace biological functions...

  • Bioreactors
  • List of omics topics in biology
The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
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