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Nigella sativa

Nigella sativa

Overview
To read about the politician, see Albert Kalonji
Albert Kalonji
Albert Kalonji is a Congolese politician best known for leading the short-lived secessionist state of South Kasai during the Congo Crisis...

.

Nigella sativa is an annual
Annual plant
An annual plant is a plant that usually germinates, flowers, and dies in a year or season. True annuals will only live longer than a year if they are prevented from setting seed...

 flowering plant
Flowering plant
The flowering plants or angiosperms are the most diverse group of land plants. The flowering plants and the gymnosperms are the only extant groups of seed plants...

, native to southwest Asia
Asia
Asia is the world's largest and most populous continent, located in the eastern and northern hemispheres. It covers 8.6% of the earth's total surface area and with approximately 4 billion people, it hosts 60% of the world's current human population.Asia is traditionally defined as part of the...

. It grows to tall, with finely divided, linear (but not thread-like) leaves
Leaf
In botany, a leaf is an above-ground plant organ specialized for photosynthesis. For this purpose, a leaf is typically flat and thin. There is continued debate about whether the flatness of leaves evolved to expose the chloroplasts to more light or to increase the absorption of carbon dioxide. In...

. The flower
Flower
A flower, sometimes known as a bloom or blossom, is the reproductive structure found in flowering plants . The biological function of a flower is to mediate the union of male sperm with female ovum in order to produce seeds...

s are delicate, and usually coloured pale blue and white, with 5–10 petals. The fruit
Fruit
The term fruit has different meanings dependent on context, and the term is not synonymous in food preparation and biology. Fruits are the means by which flowering plants disseminate seeds, and the presence of seeds indicates that a structure is most likely a fruit, though not all seeds come from...

 is a large and inflated capsule
Capsule (fruit)
In botany a capsule is a type of simple, dry fruit produced by many species of flowering plants. A capsule is a dehiscent structure composed of two or more carpels, that, at maturity, split apart to release the seeds within...

 composed of 3–7 united follicles, each containing numerous seed
Seed
A seed , referred to as a kernel in some plants, is a small embryonic plant enclosed in a covering called the seed coat, usually with some stored food. It is the product of the ripened ovule of gymnosperm and angiosperm plants which occurs after fertilization and some growth within the mother plant...

s.
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Encyclopedia
To read about the politician, see Albert Kalonji
Albert Kalonji
Albert Kalonji is a Congolese politician best known for leading the short-lived secessionist state of South Kasai during the Congo Crisis...

.

Nigella sativa is an annual
Annual plant
An annual plant is a plant that usually germinates, flowers, and dies in a year or season. True annuals will only live longer than a year if they are prevented from setting seed...

 flowering plant
Flowering plant
The flowering plants or angiosperms are the most diverse group of land plants. The flowering plants and the gymnosperms are the only extant groups of seed plants...

, native to southwest Asia
Asia
Asia is the world's largest and most populous continent, located in the eastern and northern hemispheres. It covers 8.6% of the earth's total surface area and with approximately 4 billion people, it hosts 60% of the world's current human population.Asia is traditionally defined as part of the...

. It grows to tall, with finely divided, linear (but not thread-like) leaves
Leaf
In botany, a leaf is an above-ground plant organ specialized for photosynthesis. For this purpose, a leaf is typically flat and thin. There is continued debate about whether the flatness of leaves evolved to expose the chloroplasts to more light or to increase the absorption of carbon dioxide. In...

. The flower
Flower
A flower, sometimes known as a bloom or blossom, is the reproductive structure found in flowering plants . The biological function of a flower is to mediate the union of male sperm with female ovum in order to produce seeds...

s are delicate, and usually coloured pale blue and white, with 5–10 petals. The fruit
Fruit
The term fruit has different meanings dependent on context, and the term is not synonymous in food preparation and biology. Fruits are the means by which flowering plants disseminate seeds, and the presence of seeds indicates that a structure is most likely a fruit, though not all seeds come from...

 is a large and inflated capsule
Capsule (fruit)
In botany a capsule is a type of simple, dry fruit produced by many species of flowering plants. A capsule is a dehiscent structure composed of two or more carpels, that, at maturity, split apart to release the seeds within...

 composed of 3–7 united follicles, each containing numerous seed
Seed
A seed , referred to as a kernel in some plants, is a small embryonic plant enclosed in a covering called the seed coat, usually with some stored food. It is the product of the ripened ovule of gymnosperm and angiosperm plants which occurs after fertilization and some growth within the mother plant...

s. The seed is used as a spice
Spice
A spice is a dried seed, fruit, root, bark, leaf, or vegetative substance used in nutritionally insignificant quantities as a food additive for the purpose of flavour, colour, or as a preservative that kills harmful bacteria or prevents their growth....

.

Etymology


In English
English language
English is a West Germanic language that developed in England during the Anglo-Saxon era. As a result of the military, economic, scientific, political, and cultural influence of the British Empire during the 18th, 19th, and early 20th centuries, and of the United States since the mid 20th century,...

, Nigella sativa seed is variously called fennel flower, nutmeg flower, Roman coriander, blackseed, black caraway, or black onion seed. Other names used, sometimes misleadingly, are onion seed and black sesame, both of which are similar-looking but unrelated. The seeds are frequently referred to as black cumin (as in Bengali
Bengali language
Bengali or Bangla is an Indo-Aryan language of the eastern Indian subcontinent, evolved from the Magadhi Prakrit and Sanskrit languages....

: kalo jira, kalo jeera, kali jeera), but this is also used for a different spice, Bunium persicum
Bunium persicum
Bunium persicum or black cumin is a plant in the family Apiaceae. Dried B. persicum fruits are used as a culinary spice in Northern India, Afghanistan, Tajikistan and Iran...

. The scientific name is a derivative of Latin niger "black". An older English name gith is now used for the corncockle
Agrostemma
Agrostemma is a genus of annual plants in the Caryophyllaceae family, containing the species known as corncockles. Its best-known member is A. githago, the Common Corncockle, which is a native of Europe where it is simply called "the Corncockle". The species is a weed of cereals and other crops,...

. In English-speaking countries with large immigrant populations, it is also variously known as kalonji (Hindi
Hindi
Standard Hindi, also known as High Hindi, Nagari Hindi or Literary Hindi is a standardised register of Hindi. It is one of the 22 languages with official status in India, and is used, along with English, for administration of the central government.Standard Hindi is a sanskritised register derived...

 कलौंजी kalauṃjī or कलोंजी kaloṃjī), kezah Hebrew
Hebrew language
Hebrew is a Semitic language of the Afro-Asiatic language family. Culturally, it is considered a Jewish language. Hebrew in its modern form is spoken by more than seven million people in Israel while Classical Hebrew has been used for prayer or study in Jewish communities around the world for over...

 קצח), chernushka (Russian
Russian language
Russian is the most geographically widespread language of Eurasia, the most widely spoken of the Slavic languages, and the largest native language in Europe...

), çörek otu (Turkish
Turkish language
Turkish is spoken as a first language by over 63 million people worldwide, making it the most commonly spoken of the Turkic languages. Its speakers are located predominantly in Turkey and Cyprus, with smaller groups in Iraq, Greece, Bulgaria, the Republic of Macedonia, Kosovo, Albania and other...

), habbat albarakah (Arabic
Arabic language
Arabic is a Central Semitic language, thus related to and classified alongside other Semitic languages such as Hebrew and the Neo-Aramaic languages. In terms of speakers, the Arabic macrolanguage is the largest member of the Semitic language family. It is spoken by more than 280 million people as...

 حبه البركة ḥabbatu l-barakah "seed of blessing") or siyah daneh (Persian
Persian language
Persian is an Iranian language within the Indo-Iranian branch of the Indo-European languages. It is widely spoken in Iran, Afghanistan, Tajikistan, Uzbekistan and to some extent in Iraq and Bahrain, and has a status of official language in the first three countries under different names...

 سیاه‌دانه siyâh dâne)or كلونجى in urdu. "KARIM JEERAKAM" in Malayalam.

This potpourri of vernacular names for this plant reflects that its widespread use as a spice is relatively new in the English speaking world, and largely associated with immigrants from areas where it is well known. Increasing use is likely to result in one of the names winning out.

It is used as part of the spice mixture Panch Puran and by itself in a great many recipes in Bengali cookery and most recognisably in Naan Bread as sold in the 90% of Indian Resturants in the UK which are in fact Bengali owned.

Characteristics


Nigella sativa has a pungent bitter taste and smell. It is used primarily in confectionary and liquors. The variety of naan
Naan
Naan is a leavened, oven-baked flatbread. It is one of the most popular varieties of South Asian breads and is particularly popular in Afghanistan, Iran, India, Pakistan, and the Xinjiang Autonomous Region of China, where it is considered the staple food.Originally, naan is a generic term for...

 bread called Peshawar
Peshawar
' onMouseout='HidePop("73242")' href="http://www.absoluteastronomy.com/topics/Herbalism">herbal medicine
Herbalism
Herbalism is a traditional medicinal or folk medicine practice based on the use of plants and plant extracts. Herbalism is also known as botanical medicine, medical herbalism, herbal medicine, herbology, and phytotherapy...

, Nigella sativa has antihypertensive
Antihypertensive
The antihypertensives are a class of drugs that are used to treat hypertension . Evidence suggests that reduction of the blood pressure by 5–6 mmHg can decrease the risk of stroke by 40%, of coronary heart disease by 15–20%, and reduce the likelihood of dementia, heart failure, and mortality from...

, carminative
Carminative
A carminative, also known as carminativum , is an herb or preparation that either prevents formation of gas in the gastrointestinal tract, or facilitates the expulsion of said gas, thereby combating flatulence.-Varieties:...

, and anthelmintic
Anthelmintic
Anthelmintics or antihelminthics are drugs that expel parasitic worms from the body, by either stunning or killing them. They may also be called vermifuges or vermicides .-Pharmaceutical classes:...

 properties. They are eaten by elephants to aid digestion.

History


According to Zohary and Hopf, archeological evidence about the earliest cultivation of N. sativa "is still scanty", but they report that N. sativa seeds have been found in several sites from ancient Egypt
Ancient Egypt
Ancient Egypt was an ancient civilization of eastern North Africa, concentrated along the lower reaches of the Nile River in what is now the modern country of Egypt. The civilization coalesced around 3150 BC with the political unification of Upper and Lower Egypt under the first pharaoh, and...

, including Tutankhamun
Tutankhamun
Tutankhamun , Egyptian was an Egyptian Pharaoh of the Eighteenth dynasty , during the period of Egyptian history known as the New Kingdom...

's tomb. Although its exact role in Egyptian culture is unknown, it is known that items entombed with a pharaoh
Pharaoh
Pharaoh is a title used in many modern discussions of the ancient Egyptian rulers of all periods. In antiquity this title began to be used for the ruler who was the religious and political leader of united ancient Egypt. This was true only during the New Kingdom, specifically during the middle of...

 were carefully selected to assist him in the after life.

The earliest written reference to N. sativa is thought to be in the book of Isaiah
Isaiah
Isaiah is the main figure in the Biblical Book of Isaiah, and is traditionally considered to be its author. He was an 8th-century BC Judean prophet. Part of his message was: "The land will be completely laid waste and totally plundered. The LORD has spoken this word."...

 in the Old Testament where the reaping of nigella and wheat is contrasted (Isaiah 28: 25, 27). Easton's Bible dictionary states that the Hebrew word ketsah refers to without doubt to N. sativa (although not all translations are in agreement). According to Zohary and Hopf, N. sativa "was another traditional condiment of the Old World during classical times; and its black seeds were extensively used to flavor food."

History of Medicine


Nigella sativa has been used for medicinal purposes for centuries, both as a herb and pressed into oil, in Asia, Middle East
Middle East
The Middle East is a region that spans southwestern Asia, southeastern Europe, and northeastern Africa. It has no clear boundaries, often used as a synonym to Near East, in opposition to Far East...

, and Africa
Africa
Africa is the world's second-largest and second most-populous continent, after Asia. At about 30.2 million km² including adjacent islands, it covers 6% of the Earth's total surface area and 20.4% of the total land area. With a billion people in 61 territories, it accounts for about 14.8% of the...

. It has been traditionally used for a variety of conditions and treatments related to respiratory health, stomach and intestinal health, kidney and liver function, circulatory and immune system support, and for general well-being.

In Islam
Islam
Islam Islam Islam ( al-’islām, There are ten pronunciations of Islam in English, differing in whether the first or second syllable has the stress, whether the s is or , and whether the a is pronounced as in father, as in cat, or (when the stress is on the i) as in the a of sofa...

, it is regarded as one of the greatest forms of healing medicine available. Muhammad once stated that the black seed can heal every disease—except death—as recounted in the following hadith
Hadith
Hadith are oral traditions relating to the words and deeds of the Islamic prophet Muhammad. Hadith are regarded by traditional schools of jurisprudence as important tools for determining the Muslim way of life, the sunnah. Hadith were originally oral traditions of Muhammad's actions and customs...

:
[Sahih Muslim : Book 26 Kitab As-Salam, Number 5489]

Abu Huraira (Radi Allah Anhu) reported that he heard Allah's Messenger (sal-allahu- alleihi-wasallam ) as saying: Nigella seed is a remedy for every disease except death.
[Sahih Muslim : Book 26 Kitab As-Salam, Number 5490]

Abu Huraira (Radi Allah Anhu) reported Allah's Messenger (sal-allahu- alleihi-wasallam ) as saying: There is no disease for which Nigella seed does not provide remedy.
Avicenna
Avicenna
, known as Abū Alī Sīnā or Ibn Sīnā , and commonly known in English by his Latinized name Avicenna , was a Persian polymath and the foremost physician and philosopher of his time...

, most famous for his volumes called The Canon of Medicine
The Canon of Medicine
The Canon of Medicine is a 14-volume medical encyclopedia written by Islamic scientist and physician Ibn Sīnā...

, refers to nigella as the seed that stimulates the body's energy and helps recovery from fatigue and dispiritedness. It is also included in the list of natural drugs of 'Tibb-e-Nabavi', or "Medicine of the Prophet (Muhammad)", according to the tradition "hold onto the use of the black seeds for in it is healing for all diseases except death" (Sahih Bukhari vol. 7 book 71 # 592).

In the Unani
Unani
Unani or Yunani means "Greek", and has its origins in the Greek word Ἰωνία or Ἰωνίη , a placename given to a Greek populated coastal region of Anatolia....

 Tibb system of medicine, N. sativa is regarded as a valuable remedy for a number of diseases.

The seeds have been traditionally used in the Middle East and Southeast Asia
Southeast Asia
Manila
Bangkok
Ho Chi Minh City
Kuala Lumpur
Singapore
Yangon
Bandung
Hanoi
Surabaya
Taichung
Kaohsiung
Medan|-|}...

n countries to treat ailments including asthma
Asthma
Asthma is a predisposition to chronic inflammation of the lungs in which the airways are reversibly narrowed. Asthma affects 7% of the population of the United States, and 300 million worldwide...

, bronchitis
Bronchitis
Acute bronchitis is an inflammation of the large bronchi in the lungs that is usually caused by viruses or bacteria and may last several days or weeks. Characteristic symptoms include cough, sputum production, and shortness of breath and wheezing related to the obstruction of the inflamed airways...

, rheumatism
Rheumatism
Rheumatism or rheumatic disorder is a non-specific term for medical problems affecting the joints and connective tissue. The study of, and therapeutic interventions in, such disorders is called rheumatology.-Terminology:...

 and related inflammatory diseases, to increase milk production in nursing mothers, to promote digestion and to fight parasitic infections. Its oil has been used to treat skin conditions such as eczema
Eczema
Eczema is a disease in a form of dermatitis, or inflammation of the epidermis. The term eczema is broadly applied to a range of persistent skin conditions. These include dryness and recurring skin rashes that are characterized by one or more of these symptoms: redness, skin edema , itching and...

 and boil
Boil
Boil is a skin disease caused by the infection of hair follicles, resulting in the localized accumulation of pus and dead tissue. Individual boils can cluster together and form an interconnected network of boils called carbuncles....

s and to treat cold
Common cold
Acute viral rhinopharyngitis, or acute coryza, known as an upper respiratory virus, or commonly called a cold, is a contagious, viral infectious disease of the upper respiratory system, primarily caused by rhinoviruses, or coronaviruses...

 symptoms. Its many uses have earned nigella the Arabic approbation 'Habbatul barakah', meaning the seed of blessing.

Scientific research


Black cumin oil contains nigellone, which protects guinea pig
Guinea pig
The guinea pig , also commonly called the Cavy, is a species of rodent belonging to the family Caviidae and the genus Cavia. Despite their common name, these animals are not pigs, nor do they come from Guinea...

s from histamine
Histamine
Histamine is a biogenic amine involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Histamine triggers the inflammatory response. As part of an immune response to foreign pathogens, histamine is produced by basophils and by...

-induced bronchial spasms (perhaps explaining its use to relieve the symptoms of asthma, bronchitis, and coughing
Cough
A cough , in medicine, is a sudden and often repetitively occurring defense reflex which helps to clear the large breathing passages from excess secretions, irritants, foreign particles and microbes...

).

The presence of an anti-tumor sterol
Sterol
Sterols are an important class of organic molecules. They occur naturally in plants, animals and fungi, with the most familiar type of animal sterol being cholesterol...

, beta-sitosterol
Beta-sitosterol
β-Sitosterol is one of several phytosterols with chemical structures similar to that of cholesterol. It is white in colour and waxy in nature.-Sources:...

, lends credence to its traditional use to treat abscesses and tumors of the abdomen, eyes, and liver.

Nigella sativa oil has been reported to be effective in treating opioid
Opioid
An opioid is a chemical that works by binding to opioid receptors, which are found principally in the central nervous system and the gastrointestinal tract...

 dependence.

Thymoquinone and pancreatic cancer treatment


Researchers at the Kimmel Cancer at Jefferson in Philadelphia have found that thymoquinone
Thymoquinone
Thymoquinone is a phytochemical compound found in the plant Nigella sativa. It has antioxidant effects and has been shown to protect against heart, liver and kidney damage in animal studies, as well as having possible anti-cancer effects. It also has analgesic and anticonvulsant effects in animal...

, an extract of nigella sativa seed oil, blocked pancreatic cancer
Pancreatic cancer
Pancreatic cancer is a malignant neoplasm of the pancreas. Each year in the United States, about 42,470 individuals are diagnosed with this condition and 35,240 die from the disease. The prognosis is generally poor; less than 5 percent of those diagnosed are still alive five years after diagnosis...

 cell growth and killed the cells by enhancing the process of programmed cell death, (apoptosis
Apoptosis
Apoptosis is the process of programmed cell death that may occur in multicellular organisms. Programmed cell death involves a series of biochemical events leading to a characteristic cell morphology and death; in more specific terms, a series of biochemical events that lead to a variety of...

). While the studies are in the early stages, the findings suggest that thymoquinone could eventually have some use as a preventative strategy in patients who have gone through surgery and chemotherapy or in individuals who are at a high risk of developing cancer.

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