The N-601 is a highway in central Spain

Spain

Spain , officially the Kingdom of Spain languages]] under the European Charter for Regional or Minority Languages. In each of these, Spain's official name is as follows:;;;;;;), is a country and member state of the European Union located in southwestern Europe on the Iberian Peninsula...

. It connects Madrid

Madrid

Madrid is the capital and largest city of Spain. The population of the city is roughly 3.3 million and the entire population of the Madrid metropolitan area is calculated to be 6.271 million. It is the third largest city in the European Union, after London and Berlin, and its metropolitan...

 with Leon

León, Spain

León is the capital of the province of León in the autonomous community of Castile and León, situated in the northwest of Spain. Its city population of 136,985 makes it the largest municipality in the province, accounting for more than one quarter of the province's population...

.

It starts at junction 108 km on the Autopista AP-6

Autopista AP-6

The Autopista AP-6 is a Spanish autopista route which starts in Collado Villalba and ends in Adanero .The Autopista AP-6; with toll, has a total length of 72.19 km....

 north of Madrid with a junction with N-VI

N-VI

The N-VI is a major highway in Spain. It connects Madrid to La Coruña.It has generally been up-graded or replaced by the Autovía A-6. It passes via Tordesillas, Ponferrada and Lugo....

 and N-403. The road heads north across a plain parallel to the Rio Adaja crossing the new AVE

AVE

Alta Velocidad Española is a service of high-speed rail in Spain operated by Renfe, the Spanish national railway company, at speeds of up to . The name is literally translated from Spanish as "Spanish High Speed", but also a play on the word , meaning "bird".AVE trains run on a network of...

 line before the Rio Eresma and Rio Cega. After 80 km the road arrives at Valladolid

Valladolid

Valladolid is a historic city and municipality in north-central Spain, situated at the confluence of the Pisuerga and Esgueva rivers, and located within three wine-making regions: Ribera del Duero, Rueda and Cigales...

 with the Rio Duero. There are junctions with the Autovía A-11

Autovía A-11

The Autovía A-11 is a highway in SpainIt runs between Soria and Quintanilha in Portugal in the Rio Duero valley. It supersedes the N-122.It is currently in construction....

 and Autovía A-62

Autovía A-62

The Autovía A-62 is a highway in Spain. It connects the Portuguese Border with Salamanca, Valladolid and Burgos. It is part of the European route E-80....

. Thereafter the road crosses the Montes de Torozos via Medina de Rioseco with a junction on the N-610. After a further 42 km the road reaches junction 21 of the Autovía A-231

Autovía A-231

The Autovía A-231 is a highway in Spain known as the Autovía del Camino de Santiago between Burgos and León.It is currently under construction and follows the route of the N-120 passing via Logroño and Burgos where it becomes the Autovía A-12....

. A further 20 km takes the road into Leon. The road here meets the Autopista AP-71

Autopista AP-71

The Autopista AP-71 is a highway in the province of Leon, Spain. It connects the cities of Astorga and Leon.It starts at a junction with the Autovía A-6 and heads north east parallel to the N-120 to Leon and the Autovía A-66 south west of the city....

 and Autovía A-66

Autovía A-66

The Autovía A-66 is a major highway in western Spain. It also forms part of the European Route E803. The road is an upgrade of the N-630 which is being undertaken section by section. The route roughly corresponds to the ancient Roman 'Silver Route' from the mines of northern Spain to the...

 as well as N-630.