MAP2K5
Encyclopedia
Dual specificity mitogen-activated protein kinase kinase 5 is an enzyme
that in humans is encoded by the MAP2K5 gene
.
with MAPK7
, MAP3K2
, Protein kinase Mζ and MAP3K3
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the MAP2K5 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Upstream
This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs).Interactions
MAP2K5 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with MAPK7
MAPK7
Mitogen-activated protein kinase 7 also known as MAP kinase 7 is an enzyme that in humans is encoded by the MAPK7 gene.- Function :MAPK7 is a member of the MAP kinase family...
, MAP3K2
MAP3K2
Mitogen-activated protein kinase kinase kinase 2 is an enzyme that in humans is encoded by the MAP3K2 gene.-Interactions:MAP3K2 has been shown to interact with SH2D2A, MAP2K7, MAP2K5, XIAP and MAPK8.-Further reading:...
, Protein kinase Mζ and MAP3K3
MAP3K3
Mitogen-activated protein kinase kinase kinase 3 is an enzyme that in humans is encoded by the MAP3K3 gene.-Interactions:MAP3K3 has been shown to interact with [SQSTM1/p62], MAP2K5, YWHAE, GAB1 and BRCA1.-Further reading:...
.