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Listerine

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Listerine



 
 
Listerine is a brand name for antiseptic
Antiseptic

Antiseptics are antimicrobials that are applied to living biological tissue/skin to reduce the possibility of infection, sepsis, or putrefaction....
 mouthwash
Mouthwash

Mouthwash or mouth rinse is a product used for oral hygiene. Antiseptic and anti-plaque mouth rinse claims to kill the plaque causing Dental caries, gingivitis, and bad breath....
. Its original formula has notoriously strong flavor
Flavor

Flavor or flavour is the sensory impression of a food or other chemical substance, and is determined mainly by the chemical senses of taste and olfaction....
, although variations have been released that are marketed as tasting milder. The product is marketed under the slogan "Kills germ
Microorganism

A microorganism or microbe is an organism that is microscopic . The study of microorganisms is called microbiology, a subject that began with Anton van Leeuwenhoek's discovery of microorganisms in 1675, using a microscope of his own design....
s that cause bad breath".

Listerine is one of the most popular mouthwashes sold in the United States.






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Listerine Products
Listerine is a brand name for antiseptic
Antiseptic

Antiseptics are antimicrobials that are applied to living biological tissue/skin to reduce the possibility of infection, sepsis, or putrefaction....
 mouthwash
Mouthwash

Mouthwash or mouth rinse is a product used for oral hygiene. Antiseptic and anti-plaque mouth rinse claims to kill the plaque causing Dental caries, gingivitis, and bad breath....
. Its original formula has notoriously strong flavor
Flavor

Flavor or flavour is the sensory impression of a food or other chemical substance, and is determined mainly by the chemical senses of taste and olfaction....
, although variations have been released that are marketed as tasting milder. The product is marketed under the slogan "Kills germ
Microorganism

A microorganism or microbe is an organism that is microscopic . The study of microorganisms is called microbiology, a subject that began with Anton van Leeuwenhoek's discovery of microorganisms in 1675, using a microscope of his own design....
s that cause bad breath".

Listerine is one of the most popular mouthwashes sold in the United States. It is currently manufactured and distributed by Johnson and Johnson since that company's acquisition
Mergers and acquisitions

The phrase mergers and acquisitions refers to the aspect of corporate strategy, corporate finance and management dealing with the buying, selling and combining of different corporation that can aid, finance, or help a growing company in a given industry grow rapidly without having to create another business entity....
 of Pfizer
Pfizer

Pfizer Incorporated is a major pharmaceutical company, ranking number one in sales in the world. The company is based in New York City, and its research headquarters is in Groton, Connecticut....
's consumer healthcare division in late December of 2006.

The Listerine brand name is also used on toothpaste
Toothpaste

Toothpaste is a paste or gel dentifrice used to clean and maintain the aesthetics and health of teeth. Toothpaste is used to promote oral hygiene: it can aid in the removal of dental plaque and food from the teeth, aid in the elimination and/or masking of halitosis and deliver active ingredients such as fluoride or xylitol to prevent tooth...
, Listerine Whitening rinse, new Listerine Fluoride rinse (Listerine Tooth Defense), Listerine Agent Cool Blue (children's plaque disclosing rinse), PocketPaks, and PocketMist. In September 2007, Listerine began selling their own brand of self-dissolving teeth whitening strips.

History

First formulated by Dr. Joseph Lawrence and Jordan Wheat Lambert in 1879 as surgical
Surgery

Surgery is a medical specialty that uses operative manual and instrumental techniques on a patient to investigate and/or treat a pathological condition such as disease or injury, to help improve bodily function or appearance, or sometimes for some other reason....
 antiseptic
Antiseptic

Antiseptics are antimicrobials that are applied to living biological tissue/skin to reduce the possibility of infection, sepsis, or putrefaction....
, it was given to dentists for oral care in 1895 and it was the first over-the-counter mouthwash sold in the United States in 1914. The mouthwash was named in honor of Dr. Joseph Lister, pioneer of antiseptic surgery.

According to Freakonomics
Freakonomics

Freakonomics: A Rogue Economist Explores the Hidden Side of Everything is a 2005 non-fiction book by University of Chicago economist Steven Levitt and New York Times journalist Stephen J....
,
Listerine was invented in the 19th century as powerful surgical antiseptic. It was later sold, in very distilled form, as floor cleaner and cure for gonorrhea
Gonorrhea

Gonorrhea is caused by the bacterium Neisseria gonorrhoeae and is a common sexually transmitted infection. In the US, its incidence is second only to Chlamydia infection....
. But it wasn't runaway success until the 1920s, when it was pitched as solution for "chronic halitosis", the faux medical term that the Listerine advertising group created in 1921 to describe bad breath. By naming and thus creating medical condition
Medical condition

A medical condition is a general term used to describe an observation made that can have an impact on the health of an individual.The term is sometimes used when a study encompasses a diverse variety of clinical entities, such as in the evaluation of generalist care....
 for which consumers now felt they needed cure, Listerine created market for their mouthwash. Until that time, bad breath was not conventionally considered catastrophe, but Listerine's ad campaign changed that. As the advertising scholar James B. Twitchell writes, "Listerine did not make mouthwash as much as it made halitosis." Listerine's new ads featured forlorn young women and men, eager for marriage but turned off by their mate's rotten breath. "Can I be happy with him in spite of that?" one maiden asked herself. In just seven years, the company's revenues rose from $115,000 to more than $8 million.


From 1921 until the mid-1970s Listerine was also marketed as preventive and remedy for cold
Common cold

Acute viral rhinopharyngitis, or acute coryza, usually known as the common cold, is a highly contagious, virus infectious disease of the upper respiratory system, primarily caused by picornaviruses or coronaviruses....
s and sore throat
Sore Throat

Sore Throat were a United Kingdom crust punk / grindcore band, formed in Yorkshire in 1987. They are known for being one of the earliest exponents of the grindcore subgenre known as "noisecore", as well launching the careers of several prominent members of the British heavy metal music community....
s. In 1976, the Federal Trade Commission
Federal Trade Commission

The Federal Trade Commission is an Independent agencies of the United States government, established in 1914 by the Federal Trade Commission Act....
 ruled that these claims were misleading, and that Listerine had "no efficacy" at either preventing or alleviating the symptoms of sore throats and colds. Warner-Lambert was ordered to stop making the claims, and to include in the next $10.2 million dollars' of Listerine ads specific mention that "contrary to prior advertising, Listerine will not help prevent colds or sore throats or lessen their severity."

1930s advertisements claimed that applying Listerine to the scalp could prevent dandruff.

Listerine was packaged in glass bottle inside corrugated cardboard tube for nearly 80 years before the first revamps were made to the brand; in 1992, Cool Mint Listerine was introduced in addition to the original Listerine Antiseptic formula and, in 1994, both brands were introduced in plastic bottles for the first time. In 1995, FreshBurst was added, then in 2003 Natural Citrus. In 2006 a new addition to the "less intense" variety, Vanilla Mint, was released. Currently, eight different kinds of Listerine are on the market in the U.S. and elsewhere: Original, Cool Mint, FreshBurst, Natural Citrus, Vanilla Mint, Advanced with Tartar Control (Arctic mint), Tooth Defense (mint shield), and Whitening pre-brush rinse (clean mint). The most recent addition is the Listerine Total Care, marketed as the Most Complete Listerine. It claims to reduce plaque, strengthen teeth to prevent cavities, prevent tartar build-up to keep teeth white, prevent gingivitis, and freshen breath for up to 12 hours.

Composition


The active ingredients listed on Listerine bottles are menthol
Menthol

Menthol is an organic compound #Production or obtained from peppermint or other Mentha oils. It is a waxy, crystalline substance, clear or white in color, which is solid at room temperature and melts slightly above....
, thymol
Thymol

Thymol also known as isopropylmethylphenol, is a monoterpene phenols derivative of cymene, C10H14OH, isomeric with carvacrol, found in oil of thyme, and Liquid-liquid extraction as a white crystalline substance of a pleasant aromatic odor and strong antiseptic properties....
, methyl salicylate
Methyl salicylate

Methyl salicylate is a natural product of many species of plants. Some of the plants producing it are called wintergreens, hence the common name....
, and eucalyptol
Eucalyptol

Eucalyptol is a natural organic compound which is a colorless liquid. It is a cyclic ether and a monoterpenoid.Eucalyptol is also known by a variety of synonyms: 1,8-cineol, 1,8-cineole, limonene oxide, cajeputol, 1,8-epoxy-p-menthane, 1,8-oxido-p-menthane, eucalyptol, eucalyptole, 1,3,3-trimethyl-2-oxabicyclo[2,2,2]octane, cineol, cineole...
. Ethanol
Ethanol

Ethanol, also called ethyl alcohol, pure alcohol, grain alcohol, or drinking alcohol, is a volatility , flammable, colorless liquid....
 is present in concentrations of 21.6% in the flavored product and 26.9% in the original gold Listerine Antiseptic. Thymol is an antiseptic, methyl salicylate is cleaning agent, and menthol is local anesthetic. At this concentration, the ethanol serves to dissolve the active ingredients. Contrary to persistant myths, methanol
Methanol

Methanol, also known as methyl alcohol, carbinol, wood alcohol, wood naphtha or wood spirits, is a chemical compound with chemical formula carbonhydrogen3oxygenhydrogen ....
 (which is frequently confused with menthol) is not an ingredient.

A Food and Drug Administration
Food and Drug Administration

The U.S. Food and Drug Administration is an Government agency of the United States Department of Health and Human Services and is responsible for regulating and supervising the safety of foods, dietary supplements, Medications, vaccines, Biopharmaceutical, blood transfusion, medical devices, Electromagnetic radiation-emitting devices, veteri...
 Advisory Panel has recommended that the active ingredients in Listerine be classified as Category I (safe and effective) for antiplaque and GAME antigingivitis activity.

The efficacy of the treatment is due mainly to Listerine's liquid properties, as liquids are quite effective at coating most exposed surfaces in the mouth, even between teeth. By the same coin, however, this treatment is generally ineffective at physically removing the plaque buildup and wedged-in food particles that it is intended to neutralize. Listerine is best used in conjunction with brushing and flossing, but not as a replacement .

Effectiveness

Additional rinsing helps in reducing dental plaque
Dental plaque

Dental plaque is biofilm that builds up on the teeth. If not removed regularly, it can lead to dental cavities or periodontal problems .The microorganisms that form the biofilm are almost entirely bacteria , with the composition varying by location in the mouth....
 and gingivitis
Gingivitis

Gingivitis around the teeth is a general term for gingival diseases affecting the gingiva . As generally used, the term gingivitis refers to gingival inflammation induced by bacterial biofilms adherent to tooth surfaces....
 in children, in addition to reducing the risk of bleeding from the gingival sulcus
Gingival sulcus

The gingival sulcus is an area of potential space between a tooth and the surrounding gingiva and is lined by sulcular epithelium. The depth of the sulcus is bounded by two entities: Commonly used terms of relationship and comparison in dentistry by the gingival fibers of the connective tissue attachment and Commonly used terms of relatio...
. However, the effect is not as essential as motivation to using Listerine as everyday oral hygiene
Oral hygiene

Teeth cleaning is the removal of dental plaque from teeth, in order to prevent Dental caries , gingivitis, and Periodontal disease. It is part of a complete program of oral hygiene....
. (The label of the new whitening pre-rinse recommends consumers use one of the other Listerine formulas for fighting plaque.)

In a January 6, 2005 decision, Judge Chin of the United States District Court for the Southern District of New York
United States District Court for the Southern District of New York

The United States District Court for the Southern District of New York is the United States district court whose jurisdiction comprises the following counties: Manhattan , The Bronx, Westchester County, New York, Putnam County, New York, Rockland County, New York, Orange County, New York, Dutchess County, New York, and Sullivan County, New...
 ruled that an advertising campaign by Pfizer
Pfizer

Pfizer Incorporated is a major pharmaceutical company, ranking number one in sales in the world. The company is based in New York City, and its research headquarters is in Groton, Connecticut....
, claiming that the mouthwash Listerine is as effective as flossing in fighting tooth and gum decay, is false and misleading and poses a public health risk.

Safety


Several studies have found that there is no evidence that Listerine's properties as solvent
Solvent

A solvent is a liquid or gas that dissolves a solid, liquid, or gaseous solute, resulting in a solution.The most common solvent in everyday life is water....
, mainly from the 21.6% or 26.9% (in original Gold Listerine) ethanol
Ethanol

Ethanol, also called ethyl alcohol, pure alcohol, grain alcohol, or drinking alcohol, is a volatility , flammable, colorless liquid....
, cause an easier reception of carcinogen
Carcinogen

The term carcinogen refers to any substance, radionuclide or radiation that is an agent directly involved in the promotion of cancer or in the increase of its propagation....
s. In other words, repeated use of Listerine does not increase the risk of oral cancer
Oral cancer

Oral cancer is any cancerous tissue growth located in the mouth. It may arise as a primary lesion originating in any of the oral tissues, by metastasis from a distant site of origin, or by extension from a neighboring anatomic structure, such as the nasal cavity or the maxillary sinus....
. Both the American Dental Association
American Dental Association

The American Dental Association is an American professional association established in 1859 and has more than 152,000 members. Based in Chicago, the ADA is the world's largest and oldest national dental association and promotes good oral health to the public while representing the dental profession....
 (ADA) and the United States National Cancer Institute
National Cancer Institute

The National Cancer Institute is part of the United States Federal government's National Institutes of Health. The NCI is a federally funded research and development center, one of eight agencies that compose the United States Public Health Service in the United States Department of Health and Human Services....
 (NCI) agree that the alcohol contained in antiseptic mouthwash is safe and not a factor in oral cancers. Studies conduced in 1985, 1995, and 2003 summarize that alcohol-containing mouth rinses are not associated with oral cancer. However, an extensive study published December 2008 in the Australian Dental Journal concluded that:


Andrew Penman, chief executive of The Cancer Council New South Wales
The Cancer Council New South Wales

The Cancer Council New South Wales is an independent, community-funded organisation dedicated to the defeat of cancer. Based in Sydney in the state of New South Wales, Australia, its main activities include: cancer prevention and education campaigns; advocacy; patient support and information services; and epidemiological and psychosocial re...
, called for further research on the matter.

On April 11 2007 McNeil-PPC disclosed that there were potentially contaminants in all Listerine Agent Cool Blue products sold since its launch in 2006, and that all bottles were being recalled. The recall affects some 4,000,000 bottles sold since that time. According to the company, Listerine Agent Cool Blue is the only product affected by the safety issue and that no other products in the Listerine family were under recall.

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