Langerhans cell sarcoma
Encyclopedia
Langerhans cell sarcoma is a form of malignant histiocytosis
. It should not be confused with Langerhans cell histiocytosis
, which is cytologically benign. Langerhans cell sarcoma is known to transform into leukemia. It can present in the lung
, but such cases are rare.
Malignant histiocytosis
Malignant histiocytosis is a rare hereditary disease found in the Bernese Mountain Dog and humans, characterized by histiocytic infiltration of the lungs and lymph nodes. The liver, spleen, and central nervous system can also be affected. Histiocytes are a component of the immune system that...
. It should not be confused with Langerhans cell histiocytosis
Langerhans cell histiocytosis
Langerhans cell Histiocytosis is a rare disease involving clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes...
, which is cytologically benign. Langerhans cell sarcoma is known to transform into leukemia. It can present in the lung
Lung
The lung is the essential respiration organ in many air-breathing animals, including most tetrapods, a few fish and a few snails. In mammals and the more complex life forms, the two lungs are located near the backbone on either side of the heart...
, but such cases are rare.