L-759,633
Encyclopedia
L-759,633 is an analgesic
drug which is a cannabinoid agonist
. It is a fairly selective agonist for the CB2 receptor
, with selectivity of 163x for CB2 over CB1.
It produces some similar effects to other cannabinoid agonists such as analgesia, but with little or no sedative
or psychoactive effects due to its weak CB1 activity, and a relatively strong antiinflammatory effect due to its strong activity at CB2.
Analgesic
An analgesic is any member of the group of drugs used to relieve pain . The word analgesic derives from Greek an- and algos ....
drug which is a cannabinoid agonist
Agonist
An agonist is a chemical that binds to a receptor of a cell and triggers a response by that cell. Agonists often mimic the action of a naturally occurring substance...
. It is a fairly selective agonist for the CB2 receptor
Receptor (biochemistry)
In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism...
, with selectivity of 163x for CB2 over CB1.
It produces some similar effects to other cannabinoid agonists such as analgesia, but with little or no sedative
Sedative
A sedative or tranquilizer is a substance that induces sedation by reducing irritability or excitement....
or psychoactive effects due to its weak CB1 activity, and a relatively strong antiinflammatory effect due to its strong activity at CB2.