John Savill
Encyclopedia
Sir John Stewart Savill is the Chief Executive of the Medical Research Council (UK)
Medical Research Council (UK)
The Medical Research Council is a publicly-funded agency responsible for co-ordinating and funding medical research in the United Kingdom. It is one of seven Research Councils in the UK and is answerable to, although politically independent from, the Department for Business, Innovation and Skills...

, having previously been appointed as the Head of the College of Medicine and Veterinary Medicine
University of Edinburgh Medical School
The University of Edinburgh Medical School is part of the College of Medicine and Veterinary Medicine of the University of Edinburgh. Established nearly 283 years ago, Edinburgh Medical School is one of the oldest medical schools in Scotland and the UK...

 and a Vice Principal of the University of Edinburgh
University of Edinburgh
The University of Edinburgh, founded in 1583, is a public research university located in Edinburgh, the capital of Scotland, and a UNESCO World Heritage Site. The university is deeply embedded in the fabric of the city, with many of the buildings in the historic Old Town belonging to the university...

.

Savill remains active in acute general medicine and is an Honorary Consultant Physician and Nephrologist with the Lothian University Hospitals Division. He is a member of the Lothian Health Board and chairs its Service Redesign Committee.

Savill has extensive experience in peer review and has a particular interest in research and development, and the career structures necessary for this, having chaired the Academy of Medical Sciences Working Party on Clinical Academic Careers.

He was knighted
Knight Bachelor
The rank of Knight Bachelor is a part of the British honours system. It is the most basic rank of a man who has been knighted by the monarch but not as a member of one of the organised Orders of Chivalry...

 in the 2008 New Year Honours
New Year Honours 2008
The New Year Honours 2008 for the Commonwealth Realms were announced on 29 December 2007, to celebrate the year passed and mark the beginning of 2008....

.

Present roles

  • Vice Principal and Head of the College of Medicine and Veterinary Medicine
    University of Edinburgh Medical School
    The University of Edinburgh Medical School is part of the College of Medicine and Veterinary Medicine of the University of Edinburgh. Established nearly 283 years ago, Edinburgh Medical School is one of the oldest medical schools in Scotland and the UK...

     at the University of Edinburgh
    University of Edinburgh
    The University of Edinburgh, founded in 1583, is a public research university located in Edinburgh, the capital of Scotland, and a UNESCO World Heritage Site. The university is deeply embedded in the fabric of the city, with many of the buildings in the historic Old Town belonging to the university...

     since October 2002.
  • Professor of Experimental Medicine since 1998.
  • Chair of Medicine since 1998
  • Chairman of the Physiological Systems and Clinical Sciences Board of the MRC, and is a full member of the Council itself.

Past roles

  • Director of the Medical Research Council (MRC) and University of Edinburgh Centre for Inflammation Research, where he continues to direct a group interested in the molecular cell biology of renal inflammation.
  • Professor of Medicine since 1998, a role he vacated in 1998.

Research

John Savill's research interests revolve around the role of cell death and macrophages in resolution and repair of inflammation, especially inflammatory disorders of the kidney glomerulus (glomerulonephritis
Glomerulonephritis
Glomerulonephritis, also known as glomerular nephritis, abbreviated GN, is a renal disease characterized by inflammation of the glomeruli, or small blood vessels in the kidneys...

) and interstitium (tubulointerstitial nephritis).

Funding

The group have received grants form the following:
  • Medical Research Council Centre Grant. (Lead applicant with Professors D Harrison, C Haslett, J Lamb and N Turner) for the Edinburgh Centre in Inflammation Research. To August 2005 (£1,518,324).

  • Wellcome Trust Programme Grant. Renewal (first applicant with Dr S Brown) for “Macrophage interaction with cells dying by apoptosis and the regulation of glomerulonephritis”. From Dec 2001 for 5 years (£1,164,526).

  • Wellcome Trust Senior Research Fellowship in Clinical Science. For Dr Jeremy Hughes to study “Macrophage regulation of tubulointerstitial fate in renal injury and repair”. To July 2005 (£838,538).

  • National Kidney Research Fund Senior Fellowship. For Dr Jeremy Duffield to study “Inhibitory receptor regulation of macrophage-directed glomerular cell death”. To July 2005 (£216,000).

  • Arthritis Research Campaign Clinician Scientist Fellowship. For Dr Mohini Gray to study “Macrophage clearance of apoptotic cells and suppression of proinflammatory cytokine secretion in persistent arthritis”. To May 2006 (£461,557).

  • Wellcome Trust Clinician Scientist Fellowship. For Dr Lynda Stuart to study “Defective clearance f dying cells, aberrant dendritic cell maturation and autoimmunity”. From Feb 2004 for 4 years (£437,844).

External links

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