Isamoltane
Encyclopedia
Isamoltane is a drug
used in scientific research. It acts as an antagonist
at the β-adrenergic, 5-HT1A
, and 5-HT1B
receptor
s. It has about five times the potency for the 5-HT1B receptor (21 nmol/l) over the 5-HT1A receptor (112 nmol/l). It has anxiolytic
effects in rodents.
Drug
A drug, broadly speaking, is any substance that, when absorbed into the body of a living organism, alters normal bodily function. There is no single, precise definition, as there are different meanings in drug control law, government regulations, medicine, and colloquial usage.In pharmacology, a...
used in scientific research. It acts as an antagonist
Antagonist
An antagonist is a character, group of characters, or institution, that represents the opposition against which the protagonist must contend...
at the β-adrenergic, 5-HT1A
5-HT1A receptor
The 5-HT1A receptor is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin . It is a G protein-coupled receptor that is coupled to Gi/Go and mediates inhibitory neurotransmission...
, and 5-HT1B
5-HT1B receptor
5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene. The 5-HT1B receptor is a 5-HT receptor subtype.-Tissue distribution and function:...
receptor
Receptor (biochemistry)
In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism...
s. It has about five times the potency for the 5-HT1B receptor (21 nmol/l) over the 5-HT1A receptor (112 nmol/l). It has anxiolytic
Anxiolytic
An anxiolytic is a drug used for the treatment of anxiety, and its related psychological and physical symptoms...
effects in rodents.