Imipramine also known as melipramine, is an antidepressant

Antidepressant

An antidepressant is a psychiatric medication used to alleviate mood disorders, such as major depression and dysthymia and anxiety disorders such as social anxiety disorder. According to Gelder, Mayou &*Geddes people with a depressive illness will experience a therapeutic effect to their mood;...

 medication

Medication

A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely defined as any chemical substance intended for use in the medical diagnosis, cure, treatment, or prevention of disease.- Classification :...

, a tricyclic antidepressant

Tricyclic antidepressant

Tricyclic antidepressants are heterocyclic chemical compounds used primarily as antidepressants. The TCAs were first discovered in the early 1950s and were subsequently introduced later in the decade; they are named after their chemical structure, which contains three rings of atoms...

 of the dibenzazepine

Dibenzazepine

Dibenzazepine is a chemical compound with two benzene rings fused to an azepine group.Dibenzazepine is used as an intermediate for the synthesis of specific analgesic and antipsychotic agents....

 group. Imipramine is mainly used in the treatment of major depression and enuresis

Enuresis

Enuresis refers to an inability to control urination. Use of the term is usually limited to describing individuals old enough to be expected to exercise such control.Types of enuresis include:* Nocturnal enuresis* Diurnal enuresis...

 (inability to control urination).

It has also been evaluated for use in panic disorder

Panic disorder

Panic disorder is an anxiety disorder characterized by recurring severe panic attacks. It may also include significant behavioral change lasting at least a month and of ongoing worry about the implications or concern about having other attacks. The latter are called anticipatory attacks...

.
Imipramine was, in the late 1950s, the first tricyclic antidepressant to be developed (by Ciba). It was first tried against psychotic disorders, such as schizophrenia, but proved insufficient.