IgSF CAM
Encyclopedia
Immunoglobulin superfamily
CAMs (IgSF CAMs) are a class of cell adhesion molecule
s.
They are either homophilic or heterophilic and bind integrins or different IgSF CAMs.
Immunoglobulin superfamily
The immunoglobulin superfamily is a large group of cell surface and soluble proteins that are involved in the recognition, binding, or adhesion processes of cells. Molecules are categorized as members of this superfamily based on shared structural features with immunoglobulins ; they all possess a...
CAMs (IgSF CAMs) are a class of cell adhesion molecule
Cell adhesion molecule
Cell Adhesion Molecules are proteins located on the cell surface involved with the binding with other cells or with the extracellular matrix in the process called cell adhesion....
s.
They are either homophilic or heterophilic and bind integrins or different IgSF CAMs.
Examples
Here is a list of some molecules of this family:- SynCAMs Synaptic Cell Adhesion Molecules
- NCAMs Neural Cell Adhesion Molecules
- ICAM-1ICAM-1ICAM-1 also known as CD54 is a protein that in humans is encoded by the ICAM1 gene. This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system...
Intercellular Cell Adhesion Molecule - VCAM-1VCAM-1Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 or cluster of differentiation 106 is a protein that in humans is encoded by the VCAM1 gene...
Vascular Cell Adhesion Molecule - PECAM-1 Platelet-endothelial Cell Adhesion Molecule
- L1L1 (protein)L1, also known as L1CAM, is a transmembrane protein; it is a neuronal cell adhesion molecule, member of the L1 protein family, of 200-220 kDa, and involved in axon guidance and cell migration with a strong implication in treatment-resistant cancers....
- CHL1CHL1Neural cell adhesion molecule L1-like protein also known as close homolog of L1 is a protein that in humans is encoded by the CHL1 gene.CHL1 is a cell adhesion molecule closely related to the L1...
- MAGMyelin-associated glycoproteinMyelin-associated glycoprotein is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR. MAG is believed to be involved in myelination during nerve regeneration....
- Nectins and nectin-like moleculesNectinNectins and Nectin-like molecules are families of cellular adhesion molecules involved in Ca2+-independent cellular adhesion.Nectins are ubiquitously expressed and have adhesive roles in a wide range of tissues such as the adherens junction of epithelia or the chemical synapse of the neuronal...
- CD2CD2CD2 is a cell adhesion molecule found on the surface of T cells and natural killer cells.It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor....
- CD48CD48CD48 is a human protein encoded by the gene....
- The SIGLECSIGLECSiglecs, short for sialic acid binding Ig-like lectins are cell surface receptors and members of the immunoglobulin superfamily that recognize sugars. Their ability to recognize carbohydrates using an immunoglobulin domain places them in the group of I-type lectins...
family (e.g. CD22CD22CD22 or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells...
, CD83CD83CD83 is a human protein encoded by the gene....
) - The CTX family (e.g. CTX, JAMs, BT-IgSF, CARCoxsackie virus and adenovirus receptorCoxsackievirus and adenovirus receptor is a protein that in humans is encoded by the CXADR gene. The protein encoded by this gene is a type I membrane receptor for group B coxsackie viruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.- Function...
, VSIG, ESAMESAM (gene)Endothelial cell-selective adhesion molecule is a protein that in humans is encoded by the ESAM gene.-Further reading:...
)