IARP
Encyclopedia
International Aging Research Portfolio (IARP) is a non-profit, open-access knowledge management system incorporating grants, publications, conferences in natural and social & behavioral sciences. In addition to the advanced search and visual trend analysis tools the system includes a directory of research projects classified into categories related to aging research. The system uses automatic classification algorithms with elements of machine learning to assign research projects to the relevant categories. The directory is curated by many expert category editors and science advisory board members. The chair of the science advisory board is Dr. Charles Cantor
.
and Google Scholar
provide access to historic as well as most recent scientific abstracts and full text publications. However, few resources exist that incorporate international databases of the scientific publications, scientific grant abstracts and clinical trials databases.
Grant abstracts are usually published by the funding organizations and precede publications in peer-reviewed literature. Some of the experiments described in grant abstracts fail or do not result in peer-reviewed publications. To prevent redundancy and promote scientific cooperation it is important to browse through all available grant information worldwide to see if there are similar projects being funded.
The IARP database integrates information on research grants, peer-reviewed publications, and issued patent applications from multiple sources. Additionally, the database uses flexible project classification mechanisms and tools for analyzing project associations and trends. This system enables scientists to search the centralized project database, to classify and categorize aging projects, and to analyze the funding aspects across multiple research disciplines. The IARP is designed to provide improved allocation and prioritization of scarce research funding, to reduce project overlap and improve scientific collaboration thereby accelerating scientific and medical progress in a rapidly growing area of research.
The IARP system aggregates grant data from many sources including the US National Institutes of Health(NIH)
, European Commission(EC)
, Canadian Institutes of Health Research
, NSF
, Australian National Health and Medical Health Council
and publication abstract data through a license of MEDLINE
database. The database is searchable and the results can be presented as charts and graphs for trends analysis. One of the main features of the IARP system is automatic and manual classification of the research projects into a structured directory. The IARP science advisory board and volunteer expert category editors classify the projects from the database into relevant categories. These manually classified projects become training sets for the automatic classification algorithms with elements of machine learning.
The IARP system is highly modular and portable and may be used as a platform for developing other knowledge management systems for aging research.
, European Commission(EC)
, NSF
, Canadian and Australian research councils and many other sources. It also contains MEDLINE
article abstracts under a license from the National Library of Medicine.
The IARP volunteer development team works directly with the publication offices and regularly updates the database either automatically or by parsing the data mailed on physical medium.
IARP translates this initial search formulation and automatically adds field names, Boolean operators, and enhancing the search formulation significantly, in particular by routinely combining (using the OR operator) text words.
is translated as
. Moreover, it links the current project with other similar projects and financial mechanisms.
To use the advanced search features effectively, the user must poses some knowledge of the research area and use relevant and specific keywords and limits. The form allows users to specify multiple values for accurate data retrieval.
[Keywords]. Users can use Boolean operators and Mask for finding information in project description and title fields.
Search query examples:
[Research Areas]. Users can limit their searches by selecting desired research areas from the category tree.
[Theories Of Aging]. Users can select multiple values from a list of Theories Of Aging.
In addition, users can limit their search by:
Fiscal Years, Project Number, Principal Investigators
, Project Start and End dates, Recipient and Funding Organizations, Funding type.
and Recurrent-Neural-Network-Based Boolean Factor Analysis (BFA).
members, institute directors and laboratory heads to curate the top-level categories and delegate the management of lower-level categories to graduate students.
The Aging.CC project allows for a simple keyword search of millions of biomedical projects supported by major research funding organizations worldwide.
Charles Cantor
Charles Cantor is an American molecular geneticist who, in conjunction with David Schwartz, developed pulse field gel electrophoresis for very large DNA molecules....
.
Background
Aging research is a multidisciplinary field spanning many areas of natural and social and behavioral sciences and the research data is widely dispersed. Popular resources like PubmedPubMed
PubMed is a free database accessing primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics. The United States National Library of Medicine at the National Institutes of Health maintains the database as part of the Entrez information retrieval system...
and Google Scholar
Google Scholar
Google Scholar is a freely accessible web search engine that indexes the full text of scholarly literature across an array of publishing formats and disciplines. Released in beta in November 2004, the Google Scholar index includes most peer-reviewed online journals of Europe and America's largest...
provide access to historic as well as most recent scientific abstracts and full text publications. However, few resources exist that incorporate international databases of the scientific publications, scientific grant abstracts and clinical trials databases.
Grant abstracts are usually published by the funding organizations and precede publications in peer-reviewed literature. Some of the experiments described in grant abstracts fail or do not result in peer-reviewed publications. To prevent redundancy and promote scientific cooperation it is important to browse through all available grant information worldwide to see if there are similar projects being funded.
The IARP database integrates information on research grants, peer-reviewed publications, and issued patent applications from multiple sources. Additionally, the database uses flexible project classification mechanisms and tools for analyzing project associations and trends. This system enables scientists to search the centralized project database, to classify and categorize aging projects, and to analyze the funding aspects across multiple research disciplines. The IARP is designed to provide improved allocation and prioritization of scarce research funding, to reduce project overlap and improve scientific collaboration thereby accelerating scientific and medical progress in a rapidly growing area of research.
The IARP system aggregates grant data from many sources including the US National Institutes of Health(NIH)
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...
, European Commission(EC)
European Commission
The European Commission is the executive body of the European Union. The body is responsible for proposing legislation, implementing decisions, upholding the Union's treaties and the general day-to-day running of the Union....
, Canadian Institutes of Health Research
Canadian Institutes of Health Research
Canadian Institutes of Health Research is the major federal agency responsible for funding health research in Canada. It is the successor to the Medical Research Council of Canada. It aims to create new health knowledge, and to translate that knowledge from the research setting into real world...
, NSF
National Science Foundation
The National Science Foundation is a United States government agency that supports fundamental research and education in all the non-medical fields of science and engineering. Its medical counterpart is the National Institutes of Health...
, Australian National Health and Medical Health Council
National Health and Medical Research Council
The National Health and Medical Research Council is Australia's peak funding body for medical research, with a budget of roughly 700 million dollars a year...
and publication abstract data through a license of MEDLINE
MEDLINE
MEDLINE is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medicine, nursing, pharmacy, dentistry, veterinary medicine, and health care...
database. The database is searchable and the results can be presented as charts and graphs for trends analysis. One of the main features of the IARP system is automatic and manual classification of the research projects into a structured directory. The IARP science advisory board and volunteer expert category editors classify the projects from the database into relevant categories. These manually classified projects become training sets for the automatic classification algorithms with elements of machine learning.
The IARP system is highly modular and portable and may be used as a platform for developing other knowledge management systems for aging research.
Content
The International Aging Research Portfolio (IARP) includes historic grant data from the National Institutes of Health(NIH)National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...
, European Commission(EC)
European Commission
The European Commission is the executive body of the European Union. The body is responsible for proposing legislation, implementing decisions, upholding the Union's treaties and the general day-to-day running of the Union....
, NSF
National Science Foundation
The National Science Foundation is a United States government agency that supports fundamental research and education in all the non-medical fields of science and engineering. Its medical counterpart is the National Institutes of Health...
, Canadian and Australian research councils and many other sources. It also contains MEDLINE
MEDLINE
MEDLINE is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medicine, nursing, pharmacy, dentistry, veterinary medicine, and health care...
article abstracts under a license from the National Library of Medicine.
The IARP volunteer development team works directly with the publication offices and regularly updates the database either automatically or by parsing the data mailed on physical medium.
Simple searches
Simple searches on IARP can be carried out by entering key aspects of a subject into search window.IARP translates this initial search formulation and automatically adds field names, Boolean operators, and enhancing the search formulation significantly, in particular by routinely combining (using the OR operator) text words.
- 'Programmed Theory Aging'
is translated as
Advanced searches
Advanced Project Search allows users to limit their search criteria, ranging from the date of creation and research and funding mechanism to specific projects. In addition to the description, each research project contains specific information about the funding organization, recipient organization and the Principal Investigator(s)Principal investigator
A principal investigator is the lead scientist or engineer for a particular well-defined science project, such as a laboratory study or clinical trial....
. Moreover, it links the current project with other similar projects and financial mechanisms.
To use the advanced search features effectively, the user must poses some knowledge of the research area and use relevant and specific keywords and limits. The form allows users to specify multiple values for accurate data retrieval.
[Keywords]. Users can use Boolean operators and Mask for finding information in project description and title fields.
Search query examples:
- 'nerv*'
- 'stem AND cell NOT embryonic'
- 'accumulation amyloid alzheimers'
[Research Areas]. Users can limit their searches by selecting desired research areas from the category tree.
[Theories Of Aging]. Users can select multiple values from a list of Theories Of Aging.
In addition, users can limit their search by:
Fiscal Years, Project Number, Principal Investigators
Principal investigator
A principal investigator is the lead scientist or engineer for a particular well-defined science project, such as a laboratory study or clinical trial....
, Project Start and End dates, Recipient and Funding Organizations, Funding type.
Trends and Tools
Trends Analysis Chart & Tools is a collection of tools for visualizing the project data as diagrams, charts and comparative tables. The interface allows users to create two-dimensional charts comparing research funding by year, institution, university, principal investigator, region and category.Summary statistics
Representing a comprehensive analysis of data stored in the system (useful for understanding the content of the database by total number of projects). Displays the current state of the database is stored on publications and projects in detail : total, classified, classified manually, classified as aging, unclassified. Displays the top 50 active, completed projects by total funding, the top countries, US states, investigators, funding bodies and recipient organizations, also by total funding.Other Tools
The system also incorporates tools like the Grant Matchmaker, Who is Who and Funding Organizations and Biotechnology Events and Webcasts that are currently in various stages of development. The intent of these tools is to provide the research community with the ability to identify organizations funding similar research projects, identify possible collaborators and find conference relevant to their research interests.Automatic Project Classification
Automatic project classification is used to identify projects related to aging research within the large data sets and to classify projects into relevant semantic groups. The system utilizes two classification algorithms with elements of machine learning: Support Vector Machine SVMSupport vector machine
A support vector machine is a concept in statistics and computer science for a set of related supervised learning methods that analyze data and recognize patterns, used for classification and regression analysis...
and Recurrent-Neural-Network-Based Boolean Factor Analysis (BFA).
Manual Project Classification
As current automatic classification algorithms are limited and require each category to have relatively large training sets, the system relies heavily on manual classification by expert category editors. The SAB and Category Editor administrative interface enables SABScientific Advisory Group
The Scientific Advisory Group of the United States Air Force, later renamed the Scientific Advisory Board, was established in 1944, when General Henry H. Arnold asked Dr. Theodore von Kármán to establish a group of scientists to review the techniques and research trends in aeronautics...
members, institute directors and laboratory heads to curate the top-level categories and delegate the management of lower-level categories to graduate students.
Linking Related Grants and Publications
IARP has the ability to automatically identify related and similar projects in database using an algorithm analysis of project abstracts, patents, and publications. This type of advanced project analysis will potentially aid in circumventing project overlap and redundant funding of similar programs while also highlighting knowledge gaps for potential funding.Other Resources Using IARP Database
The FundingTrends project allows for a simple keyword search of millions of biomedical projects supported by major research funding organizations worldwide. It then draws the amount of funding for each year for the projects containing the keywords.The Aging.CC project allows for a simple keyword search of millions of biomedical projects supported by major research funding organizations worldwide.
Reviews
- The International Aging Research Portfolio was reviewed by the editorial of the Genetic Engineering & Biotechnology News (GEN) and received a three star rating .
See also
- Community Research & Development Information Service
- Computer Retrieval of Information on Scientific ProjectsComputer Retrieval of Information on Scientific ProjectsThe CRISP system at NIH has been replaced by the RePORT Expenditures and Results query tool. CRISP was a fully searchable database of biomedical research projects funded by the U.S. government...
- Australian Research CouncilAustralian Research CouncilThe Australian Research Council is the Australian Government’s main agency for allocating research funding to academics and researchers in Australian universities. Its mission is to advance Australia’s capacity to undertake research that brings economic, social and cultural benefit to the...
- National Research Council (Canada)