Holmesburg Prison
Encyclopedia
Holmesburg Prison is part of the City of Philadelphia Prison System. Built in 1896 and in continuous use until 1995, the facility is located at 8215 Torresdale Ave in the Holmesburg section of Philadelphia, Pennsylvania
Pennsylvania
The Commonwealth of Pennsylvania is a U.S. state that is located in the Northeastern and Mid-Atlantic regions of the United States. The state borders Delaware and Maryland to the south, West Virginia to the southwest, Ohio to the west, New York and Ontario, Canada, to the north, and New Jersey to...

. It was the site of a controversial decades-long dermatological, pharmaceutical, and biochemical weapons research projects involving testing on inmates,. Holmesburg Prison is also notable for several major riots
Prison riot
A prison riot is an act of concerted defiance or disorder by a group of prisoners against the prison administrators, prison officers, or other groups of prisoners in attempt to force change or express a grievance....

 in the early 1970s as well as a report released in 1968 of the results of an extensive two-year investigation by the Offices of the Philadelphia Police Commissioner and the District Attorney of Philadelphia
District Attorney of Philadelphia
The Office of the District Attorney of Philadelphia is the largest prosecutor's office in Pennsylvania, and one of the largest in the nation. It serves the more than 1.5 million citizens of the City and County of Philadelphia, Pennsylvania. The current District Attorney of Philadelphia is Seth...

 documenting hundreds of cases of the rape of inmates.

Dermatological experimentation controversy

From approximately 1951 to 1974, Holmesburg Prison was the site of a comprehensive dermatological research operation, using prisoners as subjects. Led by Dr. Albert M. Kligman of the University of Pennsylvania
University of Pennsylvania
The University of Pennsylvania is a private, Ivy League university located in Philadelphia, Pennsylvania, United States. Penn is the fourth-oldest institution of higher education in the United States,Penn is the fourth-oldest using the founding dates claimed by each institution...

 on behalf of Dow Chemical Company
Dow Chemical Company
The Dow Chemical Company is a multinational corporation headquartered in Midland, Michigan, United States. As of 2007, it is the second largest chemical manufacturer in the world by revenue and as of February 2009, the third-largest chemical company in the world by market capitalization .Dow...

 and Johnson & Johnson
Johnson & Johnson
Johnson & Johnson is an American multinational pharmaceutical, medical devices and consumer packaged goods manufacturer founded in 1886. Its common stock is a component of the Dow Jones Industrial Average and the company is listed among the Fortune 500....

, the program paid hundreds of inmates a nominal stipend to test a wide range of products and compounds, such as facial creams, moisturizers, perfumes, detergents, and anti-rash creams. In one of the studies, for which Dow Chemical paid Kligman $10,000, Kligman injected dioxin—a highly toxic, carcinogenic component of Agent Orange, which Dow was manufacturing for use in Vietnam at the time—into 70 prisoners (most of them black). The prisoners developed severe lesions which went untreated for seven months.[9] Dow Chemical wanted to study the health effects of dioxin and other herbicides, and how they affect human skin, because workers at their chemical plants were developing chloracne. In the study, Kligman applied roughly the amount of dioxin Dow employees were being exposed to. In 1980 and 1981, some of the people who were used in this study sued Professor Kligman for a variety of health problems, including lupus and psychological damage. The 1998 book Acres of Skin: Human Experiments at Holmesburg Prison, by Allen M. Hornblum, documents clinical non-therapeutic medical experiments on prison inmates at Holmesburg.

Kligman later continued his dioxin studies, increasing the dosage of dioxin he applied to 10 prisoners' skin to 7,500 micrograms of dioxin, which is 468 times the dosage that the Dow Chemical official Gerald K. Rowe had authorized him to administer. As a result, the prisoners developed inflammatory pustules and papules.[71]

The Holmesburg program also paid hundreds of inmates a nominal stipend to test a wide range of cosmetic products and chemical compounds, whose health effects were unknown at the time.[72][73] Upon his arrival at Holmesberg, Kligman is claimed to have said "All I saw before me were acres of skin ... It was like a farmer seeing a fertile field for the first time".[74] It was reported in a 1964 issue of Medical News that 9 out of 10 prisoners at Holmesburg Prison were medical test subjects.[75]

In 1967, the U.S. Army paid Kligman to apply skin-blistering chemicals to the faces and backs of inmates at Holmesburg to, in Kligman's words, "learn how the skin protects itself against chronic assault from toxic chemicals, the so-called hardening process."

In popular culture

The prison was the location for many of the scenes in the 1996 motion picture Up Close & Personal
Up Close & Personal
Up Close & Personal is an American romantic drama film directed by Jon Avnet, and starring Robert Redford as a news director and Michelle Pfeiffer as his protegée, with Stockard Channing, Joe Mantegna and Kate Nelligan in supporting roles....

.

See also

  • Human experimentation in the United States
    Human experimentation in the United States
    There have been numerous experiments performed on human test subjects in the United States that have been considered unethical, and were often performed illegally, without the knowledge, consent, or informed consent of the test subjects....

  • Acres of Skin: Human Experiments at Holmesburg Prison
  • Human radiation experiments
    Human radiation experiments
    Since the discovery of ionizing radiation, a number of human radiation experiments have been performed to understand the effects of ionizing radiation and radioactive contamination on the human body, specifically with the element plutonium....


External links

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