Hepatitis F
Encyclopedia
Hepatitis F is a hypothetical virus
Virus
A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...

 linked to hepatitis
Hepatitis
Hepatitis is a medical condition defined by the inflammation of the liver and characterized by the presence of inflammatory cells in the tissue of the organ. The name is from the Greek hepar , the root being hepat- , meaning liver, and suffix -itis, meaning "inflammation"...

. Several hepatitis F candidates emerged in the 1990s; none of these reports have been substantiated.

In 1994, Deka et al. reported that novel viral particles had been discovered in the stool of post-transfusion, non-hepatitis A
Hepatitis A
Hepatitis A is an acute infectious disease of the liver caused by the hepatitis A virus , an RNA virus, usually spread the fecal-oral route; transmitted person-to-person by ingestion of contaminated food or water or through direct contact with an infectious person...

, non-hepatitis B, non-hepatitis C
Hepatitis C
Hepatitis C is an infectious disease primarily affecting the liver, caused by the hepatitis C virus . The infection is often asymptomatic, but chronic infection can lead to scarring of the liver and ultimately to cirrhosis, which is generally apparent after many years...

, non-hepatitis E
Hepatitis E
Hepatitis E is a viral hepatitis caused by infection with a virus called hepatitis E virus . HEV is a positive-sense single-stranded RNA icosahedral virus with a 7.5 kilobase genome. HEV has a fecal-oral transmission route. It is one of five known hepatitis viruses: A, B, C, D, and E...

 patients. Injection of these particles into the bloodstream of Indian rhesus monkeys caused hepatitis, and the virus was named hepatitis F or Toga virus. Further investigations failed to confirm the existence of the virus, and it was delisted as a cause for infectious hepatitis.

A subsequently-discovered virus thought to cause hepatitis was named Hepatitis G virus, though its role in hepatitis has not been confirmed and it is now considered synonymous with GB virus C and is an "orphan virus" with no causal links to any human disease.
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