Hemophagocytosis
Encyclopedia
Hemophagocytosis is phagocytosis by histiocyte
s of erythrocytes, leukocytes, platelet
s, and their precursors in bone marrow
and other tissues.
It is part of the presentation of hemophagocytic lymphohistiocytosis
.
Histiocyte
A histiocyte is a cell that is part of the mononuclear phagocyte system . The mononuclear phagocytic system is part of the organism's immune system...
s of erythrocytes, leukocytes, platelet
Platelet
Platelets, or thrombocytes , are small,irregularly shaped clear cell fragments , 2–3 µm in diameter, which are derived from fragmentation of precursor megakaryocytes. The average lifespan of a platelet is normally just 5 to 9 days...
s, and their precursors in bone marrow
Bone marrow
Bone marrow is the flexible tissue found in the interior of bones. In humans, bone marrow in large bones produces new blood cells. On average, bone marrow constitutes 4% of the total body mass of humans; in adults weighing 65 kg , bone marrow accounts for approximately 2.6 kg...
and other tissues.
It is part of the presentation of hemophagocytic lymphohistiocytosis
Hemophagocytic lymphohistiocytosis
Hemophagocytic lymphohistiocytosis , also known as hemophagocytic syndrome, is an uncommon hematologic disorder that, typically, clinically manifests as fever, hepatosplenomegaly, lymphadenopathy, jaundice and rash, with laboratory findings of lymphocytosis and histiocytosis, and the pathologic...
.