Heat shock protein 70 (Hsp70) internal ribosome entry site (IRES)
Encyclopedia
The heat shock protein 70 (Hsp70) internal ribosome entry site (IRES) is an RNA element
that allows cap independent translation
during conditions such as heat shock and stress. It has been shown that the 216 nucleotide
long 5' UTR contains internal ribosome entry site
activity.
Cis-regulatory element
A cis-regulatory element or cis-element is a region of DNA or RNA that regulates the expression of genes located on that same molecule of DNA . This term is constructed from the Latin word cis, which means "on the same side as". These cis-regulatory elements are often binding sites for one or...
that allows cap independent translation
Translation
Translation is the communication of the meaning of a source-language text by means of an equivalent target-language text. Whereas interpreting undoubtedly antedates writing, translation began only after the appearance of written literature; there exist partial translations of the Sumerian Epic of...
during conditions such as heat shock and stress. It has been shown that the 216 nucleotide
Nucleotide
Nucleotides are molecules that, when joined together, make up the structural units of RNA and DNA. In addition, nucleotides participate in cellular signaling , and are incorporated into important cofactors of enzymatic reactions...
long 5' UTR contains internal ribosome entry site
Internal ribosome entry site
An internal ribosome entry site, abbreviated IRES, is a nucleotide sequence that allows for translation initiation in the middle of a messenger RNA sequence as part of the greater process of protein synthesis...
activity.