HSP90AA1 - AbsoluteAstronomy.com

Heat shock protein HSP 90-alpha is a protein

Protein

Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

that in humans is encoded by the HSP90AA1 gene

Gene

A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

Interactions

Heat shock protein 90kDa alpha (cytosolic), member A1 has been shown to interact

Protein-protein interaction

Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

with TGF beta receptor 2

TGF beta receptor 2

Transforming growth factor, beta receptor II is a TGF beta receptor. TGFBR2 is its human gene.It is a tumor suppressor gene.-Interactions:...

, FKBP5

FKBP5

FK506 binding protein 5, also known as FKBP5, is a protein which in humans is encoded by the FKBP5 gene.- Function :The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and...

, TGF beta receptor 1

TGF beta receptor 1

Transforming growth factor, beta receptor I is a TGF beta receptor. TGFBR1 is its human gene.-Interactions:...

, Glucocorticoid receptor

Glucocorticoid receptor

The glucocorticoid receptor also known as NR3C1 is the receptor to which cortisol and other glucocorticoids bind....

, AKT1

AKT1

RAC-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. Multiple alternatively spliced transcript variants have been found for this gene.- Function :...

, Hop

Hop (protein)

Hop, occasionally written HOP, is an abbreviation for Hsp70-Hsp90 Organizing Protein. It functions as a co-chaperone which reversibly links together the protein chaperones Hsp70 and Hsp90....

, Peroxisome proliferator-activated receptor alpha

Peroxisome proliferator-activated receptor alpha

Peroxisome proliferator-activated receptor alpha , also known as NR1C1 , is a nuclear receptor protein that in humans is encoded by the PPARA gene.- Function :...

, AHSA1

AHSA1

Activator of 90 kDa heat shock protein ATPase homolog 1 is an enzyme that in humans is encoded by the AHSA1 gene.-Interactions:AHSA1 has been shown to interact with Heat shock protein 90kDa alpha , member A1.-Further reading:...

, HSF1

HSF1

Heat shock factor protein 1 is a protein that in humans is encoded by the HSF1 gene.-Function:The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress...

, STK11

STK11

Serine/threonine kinase 11 also known as liver kinase B1 or renal carcinoma antigen NY-REN-19 is a protein kinase that in humans is encoded by the STK11 gene.-Expression:...

, C-Raf

C-Raf

RAF proto-oncogene serine/threonine-protein kinase also known as proto-oncogene c-RAF or simply c-Raf is an enzyme that in humans is encoded by the RAF1 gene. The c-Raf protein functions in the MAPK/ERK signal transduction pathway as part of a protein kinase cascade...

, ERN1

ERN1

Serine/threonine-protein kinase/endoribonuclease IRE1 is an enzyme that in humans is encoded by the ERN1 gene.-Interactions:ERN1 has been shown to interact with Heat shock protein 90kDa alpha , member A1.-Further reading:...

, PIM1

PIM1

Proto-oncogene serine/threonine-protein kinase Pim-1 is an enzyme that in humans is encoded by the PIM1 gene.Pim-1 is a proto-oncogene which encodes for the serine/threonine kinase of the same name. The pim-1 oncogene was first described in relation to murine T-cell lymphomas, as it was the locus...

, GNA12

GNA12

Guanine nucleotide-binding protein subunit alpha-12 is a protein that in humans is encoded by the GNA12 gene.-Interactions:GNA12 has been shown to interact with ARHGEF1, PPP5C, ARHGEF12, Heat shock protein 90kDa alpha , member A1 and TEC....

, Endothelial NOS

Endothelial NOS

Endothelial NOS , also known as nitric oxide synthase 3 or constitutive NOS , is an enzyme that in humans is encoded by the NOS3 gene....

, Androgen receptor

Androgen receptor

The androgen receptor , also known as NR3C4 , is a type of nuclear receptor that is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus...

, CDC37

CDC37

Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene.The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction...

, DAP3

DAP3

28S ribosomal protein S29, mitochondrial is a protein that in humans is encoded by the DAP3 gene.-Interactions:DAP3 has been shown to interact with FADD, TNFRSF10A, Glucocorticoid receptor and Heat shock protein 90kDa alpha , member A1....

, SMYD3

SMYD3

SET and MYND domain-containing protein 3 is a protein that in humans is encoded by the SMYD3 gene.-Interactions:SMYD3 has been shown to interact with Heat shock protein 90kDa alpha , member A1 and POLR2A.-Further reading:...

, Telomerase reverse transcriptase

Telomerase reverse transcriptase

Telomerase reverse transcriptase is a catalytic subunit of the enzyme telomerase. Its absence is associated with the disorder Cri du chat....

, HER2/neu

HER2/neu

HER-2 also known as proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, CD340 or p185 is an enzyme that in humans is encoded by the ERBB2 gene. Over expression of this gene is correlated with higher aggressiveness in breast cancers...

, EPRS

EPRS

Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRS gene.- Gene :Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined....

, P53

P53

p53 , is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer...

, Estrogen receptor alpha

Estrogen receptor alpha

Estrogen receptor alpha , also known as NR3A1 , is a nuclear receptor that is activated by the sex hormone estrogen...

and GUCY1B3

GUCY1B3

Guanylate cyclase soluble subunit beta-1 is an enzyme that in humans is encoded by the GUCY1B3 gene.-Interactions:GUCY1B3 has been shown to interact with Heat shock protein 90kDa alpha , member A1 and Endothelial NOS.-Further reading:...