Glycyrrhizinate beta-glucuronidase
Encyclopedia
In enzymology, a glycyrrhizinate beta-glucuronidase is an enzyme
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...

 that catalyzes
Catalysis
Catalysis is the change in rate of a chemical reaction due to the participation of a substance called a catalyst. Unlike other reagents that participate in the chemical reaction, a catalyst is not consumed by the reaction itself. A catalyst may participate in multiple chemical transformations....

 the chemical reaction
Chemical reaction
A chemical reaction is a process that leads to the transformation of one set of chemical substances to another. Chemical reactions can be either spontaneous, requiring no input of energy, or non-spontaneous, typically following the input of some type of energy, such as heat, light or electricity...


glycyrrhizinate + H2O 1,2-beta-D-glucuronosyl-D-glucuronate + glycyrrhetinate


Thus, the two substrates
Substrate (biochemistry)
In biochemistry, a substrate is a molecule upon which an enzyme acts. Enzymes catalyze chemical reactions involving the substrate. In the case of a single substrate, the substrate binds with the enzyme active site, and an enzyme-substrate complex is formed. The substrate is transformed into one or...

 of this enzyme are glycyrrhizinate and H2O
Water
Water is a chemical substance with the chemical formula H2O. A water molecule contains one oxygen and two hydrogen atoms connected by covalent bonds. Water is a liquid at ambient conditions, but it often co-exists on Earth with its solid state, ice, and gaseous state . Water also exists in a...

, whereas its two products
Product (chemistry)
Product are formed during chemical reactions as reagents are consumed. Products have lower energy than the reagents and are produced during the reaction according to the second law of thermodynamics. The released energy comes from changes in chemical bonds between atoms in reagent molecules and...

 are 1,2-beta-D-glucuronosyl-D-glucuronate and glycyrrhetinate.

This enzyme belongs to the family of hydrolase
Hydrolase
In biochemistry, a hydrolase is an enzyme that catalyzes the hydrolysis of a chemical bond. For example, an enzyme that catalyzed the following reaction is a hydrolase:-Nomenclature:...

s, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is glycyrrhizinate glucuronosylhydrolase. Other names in common use include glycyrrhizin beta-hydrolase, glycyrrhizin hydrolase, and glycyrrhizinic acid hydrolase.

See also

  • Alpha-glucuronidase
    Alpha-glucuronidase
    For beta-glucuronidase, see Beta-glucuronidaseIn enzymology, an alpha-glucuronidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are alpha-D-glucuronoside and H2O, whereas its two products are alcohol and D-glucuronate.This enzyme belongs to the family...

  • Beta-glucuronidase
  • Glucuronosyl-disulfoglucosamine glucuronidase
    Glucuronosyl-disulfoglucosamine glucuronidase
    In enzymology, a glucuronosyl-disulfoglucosamine glucuronidase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-D-glucuronosyl-N2,6-disulfo-beta-D-glucosamine and H2O, whereas its two products are D-glucuronate and N2,6-disulfo-D-glucosamine.This...

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