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Fibrosarcoma
 
 
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Fibrosarcoma (fibroblastic sarcoma) is a malignant
Malignant

Malignant is a medical term used to describe a severe and progressively worsening disease. The term is most familiar as a description of cancer....
 tumor
Tumor

A tumor or tumour is the name for a swelling or lesion formed by an abnormal growth of cells . Tumor is not synonymous with cancer. A tumor can be Benign neoplasm, Carcinoma in situ or malignant, whereas cancer is by definition malignant....
 derived from fibrous connective tissue and characterized by immature proliferating
Proliferation

The word proliferation can refer to:*Nuclear proliferation*Chemical weapon proliferation*Cell growth* The proliferative phase of wound healing...
 fibroblasts or undifferentiated anaplastic spindle cells.

tumor may present different degrees of differentiation
Differentiation

Differentiation can mean the following:* The act of finding the derivative in mathematics* Differentiated instruction in education,* Cellular differentiation in biology...
: low grade (differentiated), intermediate malignancy and high malignancy (anaplastic). Depending on this differentiation, tumor cells may resemble mature fibroblasts (spindle-shaped), secreting collagen
Collagen

Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content....
, with rare mitoses.






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Encyclopedia


Fibrosarcoma (fibroblastic sarcoma) is a malignant
Malignant

Malignant is a medical term used to describe a severe and progressively worsening disease. The term is most familiar as a description of cancer....
 tumor
Tumor

A tumor or tumour is the name for a swelling or lesion formed by an abnormal growth of cells . Tumor is not synonymous with cancer. A tumor can be Benign neoplasm, Carcinoma in situ or malignant, whereas cancer is by definition malignant....
 derived from fibrous connective tissue and characterized by immature proliferating
Proliferation

The word proliferation can refer to:*Nuclear proliferation*Chemical weapon proliferation*Cell growth* The proliferative phase of wound healing...
 fibroblasts or undifferentiated anaplastic spindle cells.

Pathology

The tumor may present different degrees of differentiation
Differentiation

Differentiation can mean the following:* The act of finding the derivative in mathematics* Differentiated instruction in education,* Cellular differentiation in biology...
: low grade (differentiated), intermediate malignancy and high malignancy (anaplastic). Depending on this differentiation, tumor cells may resemble mature fibroblasts (spindle-shaped), secreting collagen
Collagen

Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content....
, with rare mitoses. These cells are arranged in short fascicles which split and merge, giving the appearance of "fish bone". Poorly differentiated tumors consist in more atypical cells, pleomorphic, giant cells, multinucleated, numerous atypical mitoses and reduced collagen production. Presence of immature blood vessels (sarcomatous vessels lacking endothelial cells) favors the bloodstream metastasizing.

Fibrosarcoma in dogs and cats

after 4.th Fibrosarcoma OP]] Fibrosarcoma occurs most frequently in the mouth in dogs. The tumor is locally invasive, and recurs often following surgery. Radiation therapy
Radiation therapy

Radiation therapy is the medicine use of ionizing radiation as part of cancer oncology to control malignant cell s . Radiotherapy may be used for curative or Adjuvant chemotherapy cancer treatment....
 and chemotherapy
Chemotherapy

Chemotherapy, in its most general sense, refers to treatment of disease by chemicals that kill cells, specifically those of micro-organisms or cancer....
 are also used in treatment. Fibrosarcoma is also a rare bone tumor in dogs.

In cats, fibrosarcoma occurs on the skin. It is also the most common vaccine-associated sarcoma
Vaccine-associated sarcoma

A vaccine-associated sarcoma is a type of malignancy tumor found in cats that has been linked to certain vaccines. VAS has become a concern for veterinarians and cat owners alike and has resulted in changes in recommended vaccine protocols....
.

See also

  • Fibrous connective tissue
    Fibrous connective tissue

    In zootomy, fibrous connective tissue is a type of connective tissue which has relatively high tensile strength, due to a relatively high concentration of collagen or elastin fibers....
  • Fibroma
    Fibroma

    Fibromas are benign tumors that are composed of fibrous or connective tissue. They can grow in all organs, arising from mesenchyme tissue. The term "fibroblastic" or "fibromatous" is used to describe tumors of the fibrous connective tissue....
  • Neurofibrosarcoma
    Neurofibrosarcoma

    Neurofibrosarcoma is a type of tumor combining characteristics of neurofibroma and fibrosarcoma.Neurofibrosarcoma, also known as peripheral nerve sheath tumor, malignant schwannoma, malignant nerve sheath tumor, and neurogenic sarcoma, is a type of cancer that causes malignant tumors in areas surrounding peripheral nerves....


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