Eutomer
Encyclopedia
The eutomer is the molecular chiral
enantiomer
having the desired bioactivity, e. g. as as an active ingredient in a drug. On the other hand the enantiomer of the eutomer having the undesired bioactivity is called distomer
.
When a compound possesses one chiral
center, it can either be racemic
or a single enantiomer
.
It is often the case that only a single one of the enantiomers contains all of the wanted bioactivity, the distomer
is often less active, has no disired activity or may even be toxic.
The sum of the difference between the two is called the eudysmic ratio
.
Chirality (chemistry)
A chiral molecule is a type of molecule that lacks an internal plane of symmetry and thus has a non-superimposable mirror image. The feature that is most often the cause of chirality in molecules is the presence of an asymmetric carbon atom....
enantiomer
Enantiomer
In chemistry, an enantiomer is one of two stereoisomers that are mirror images of each other that are non-superposable , much as one's left and right hands are the same except for opposite orientation. It can be clearly understood if you try to place your hands one over the other without...
having the desired bioactivity, e. g. as as an active ingredient in a drug. On the other hand the enantiomer of the eutomer having the undesired bioactivity is called distomer
Distomer
The distomer is an enantiomer in an optically active compound. It is often the case that only a single one of the enantiomers contains all of the wanted bioactivity, the distomer is often less active, has no disired activity or may even be toxic....
.
When a compound possesses one chiral
Chirality (chemistry)
A chiral molecule is a type of molecule that lacks an internal plane of symmetry and thus has a non-superimposable mirror image. The feature that is most often the cause of chirality in molecules is the presence of an asymmetric carbon atom....
center, it can either be racemic
Racemic
In chemistry, a racemic mixture, or racemate , is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule. The first known racemic mixture was "racemic acid", which Louis Pasteur found to be a mixture of the two enantiomeric isomers of tartaric acid.- Nomenclature :A...
or a single enantiomer
Enantiomer
In chemistry, an enantiomer is one of two stereoisomers that are mirror images of each other that are non-superposable , much as one's left and right hands are the same except for opposite orientation. It can be clearly understood if you try to place your hands one over the other without...
.
It is often the case that only a single one of the enantiomers contains all of the wanted bioactivity, the distomer
Distomer
The distomer is an enantiomer in an optically active compound. It is often the case that only a single one of the enantiomers contains all of the wanted bioactivity, the distomer is often less active, has no disired activity or may even be toxic....
is often less active, has no disired activity or may even be toxic.
The sum of the difference between the two is called the eudysmic ratio
Eudysmic ratio
The Eudysmic ratio is a common term in pharmacology, chemistry, and molecular biology. The eudysmic ratio describes the difference in pharmacologic activity between the two enantiomers of a drug....
.