Erythropoiesis-stimulating agent
Encyclopedia
Erythropoiesis-stimulating agent, commonly abbreviated ESA, an agent similar to the cytokine (erythropoetin) that stimulates red blood cell
production (erythropoeisis). ESAs, structurally
and biological
ly, are similar to naturally occurring protein
erythropoietin
.
Red blood cell
Red blood cells are the most common type of blood cell and the vertebrate organism's principal means of delivering oxygen to the body tissues via the blood flow through the circulatory system...
production (erythropoeisis). ESAs, structurally
Chemical structure
A chemical structure includes molecular geometry, electronic structure and crystal structure of molecules. Molecular geometry refers to the spatial arrangement of atoms in a molecule and the chemical bonds that hold the atoms together. Molecular geometry can range from the very simple, such as...
and biological
Biological process
A biological process is a process of a living organism. Biological processes are made up of any number of chemical reactions or other events that results in a transformation....
ly, are similar to naturally occurring protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
erythropoietin
Erythropoietin
Erythropoietin, or its alternatives erythropoetin or erthropoyetin or EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production...
.
- ErythropoietinErythropoietinErythropoietin, or its alternatives erythropoetin or erthropoyetin or EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production...
(Epo) - Epoetin alfaEpoetin alfaEpoetin alfa is human erythropoietin produced in cell culture using recombinant DNA technology. It stimulates erythropoiesis and is used to treat anemia, commonly associated with chronic renal failure and cancer chemotherapy. Epoetin is marketed under the trade names Procrit and Epogen. Its...
(Procrit/Epogen) - Epoetin betaEpoetin betaEpoetin beta is a synthetic, recombinant form of erythropoietin. It stimulates erythropoiesis and is used to treat anemia, commonly associated with chronic renal failure and cancer chemotherapy....
(NeoRecormon) - Darbepoetin alfaDarbepoetin alfaDarbepoetin alfa is a synthetic form of erythropoietin. It stimulates erythropoiesis and is used to treat anemia, commonly associated with chronic renal failure and cancer chemotherapy...
(Aranesp) - Methoxy polyethylene glycol-epoetin betaMethoxy polyethylene glycol-epoetin betaMethoxy polyethylene glycol-epoetin beta is the active ingredient of a drug marketed by Hoffmann-La Roche under the brand name Mircera. Mircera is a long-acting erythropoietin receptor activator indicated for the treatment of patients with anaemia associated with chronic kidney disease. It is the...
(Mircera)