Enterobacteria greA leader
Encyclopedia
The Enterobacteria greA leader is a putative attenuator element identified by bioinformatics
within bacteria of the γ-proteobacterial Enterobacteriales order. It is located upstream of the rnk gene, encoding a transcription elongation factor
, and presents a Rho-independent terminator
at the 3' end. This RNA
is presumed to operate as a non-coding leader, which regulatory mechanism remains to be elucidated. Interestingly, the short abortive form of the greA transcript may also play a role as an independent sRNA: Potrykus et al. have shown that its overexpression leads to the repression of several genes. The motif might be related to other rnk leaders such as the Pseudomonas rnk leader
and the Enterobacteria rnk leader
.
Bioinformatics
Bioinformatics is the application of computer science and information technology to the field of biology and medicine. Bioinformatics deals with algorithms, databases and information systems, web technologies, artificial intelligence and soft computing, information and computation theory, software...
within bacteria of the γ-proteobacterial Enterobacteriales order. It is located upstream of the rnk gene, encoding a transcription elongation factor
Elongation factor
Elongation factors are a set of proteins that facilitate the events of translational elongation, the steps in protein synthesis from the formation of the first peptide bond to the formation of the last one.Elongation is the most rapid step in translation:...
, and presents a Rho-independent terminator
Intrinsic termination
Intrinsic termination is a mechanism in prokaryotes that causes mRNA transcription to be stopped. In this mechanism, the mRNA contains a sequence that can base pair with itself to form a stem-loop structure 7-20 base pairs in length that is also rich in cytosine-guanine base pairs...
at the 3' end. This RNA
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....
is presumed to operate as a non-coding leader, which regulatory mechanism remains to be elucidated. Interestingly, the short abortive form of the greA transcript may also play a role as an independent sRNA: Potrykus et al. have shown that its overexpression leads to the repression of several genes. The motif might be related to other rnk leaders such as the Pseudomonas rnk leader
Pseudomonas rnk leader
The Pseudomonas rnk leader is a putative attenuator element identified by bioinformatics within bacteria of the γ-proteobacterial Pseudomonas genus. It is located upstream of the rnk gene, encoding a nucleoside diphosphate kinase regulator, and presents a Rho-independent terminator at the 3' end...
and the Enterobacteria rnk leader
Enterobacteria rnk leader
The Enterobacteria rnk leader is a putative attenuator element identified by bioinformatics within bacteria of the γ-proteobacterial Enterobacteriales order. It is located upstream of the rnk gene, encoding a nucleoside diphosphate kinase regulator, and presents a Rho-independent terminator at the...
.