David J E Callaway
Encyclopedia
David J. E. Callaway is a biological nanophysicist in the New York University School of Medicine
, where he is Professor and Laboratory Director. He was trained as a theoretical physicist by Richard Feynman
and Cosmas Zachos
, and was previously an Associate Professor at the Rockefeller University
. Recently Callaway's laboratory discovered potential new therapeutics for Alzheimer's disease
based upon apomorphine
.
An earlier paper of his developing models of Alzheimer amyloid formation,
has been cited over 177 times in the Scopus
database. He has also initiated
the study of protein domain dynamics by neutron spin echo
spectroscopy, providing a way to observe protein nanomachines in motion.
Previous work includes the invention of the microcanonical ensemble
approach to lattice gauge theory
with Aneesur Rahman
, cited over 100 times, work on the convexity of the effective potential of quantum field theory
, and work on Langevin dynamics
in quantum field theory with John R. Klauder
.
A monograph
discussing Quantum triviality
and whether an elementary scalar Higgs boson
can exist was cited over 123 times in the HEP database. Another paper of his providing constraints on the Higgs boson has been cited over 103 times in that database as well. He has also published well-cited papers on topics including black holes, superconductors and protein
chemistry.
Callaway is an avid expedition mountaineer and polar explorer.
and on the PubMed database
New York University School of Medicine
The New York University School of Medicine is one of the graduate schools of New York University. Founded in 1841 as the University Medical College, the NYU School of Medicine is one of the foremost medical schools in the United States....
, where he is Professor and Laboratory Director. He was trained as a theoretical physicist by Richard Feynman
Richard Feynman
Richard Phillips Feynman was an American physicist known for his work in the path integral formulation of quantum mechanics, the theory of quantum electrodynamics and the physics of the superfluidity of supercooled liquid helium, as well as in particle physics...
and Cosmas Zachos
Cosmas Zachos
Cosmas K. Zachos is a theoretical physicist. He was educated in physics at Princeton University, and did graduate work in theoretical physics at the California Institute of Technology under the supervision of John Henry Schwarz.Zachos is a staff member in the theory group of the High Energy...
, and was previously an Associate Professor at the Rockefeller University
Rockefeller University
The Rockefeller University is a private university offering postgraduate and postdoctoral education. It has a strong concentration in the biological sciences. It is also known for producing numerous Nobel laureates...
. Recently Callaway's laboratory discovered potential new therapeutics for Alzheimer's disease
Alzheimer's disease
Alzheimer's disease also known in medical literature as Alzheimer disease is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death...
based upon apomorphine
Apomorphine
Apomorphine is a non-selective dopamine agonist which activates both D1-like and D2-like receptors, with some preference for the latter subtypes. It is historically a morphine decomposition product by boiling with concentrated acid, hence the -morphine suffix...
.
An earlier paper of his developing models of Alzheimer amyloid formation,
has been cited over 177 times in the Scopus
Scopus
Scopus, officially named SciVerse Scopus, is a bibliographic database containing abstracts and citations for academic journal articles. It covers nearly 18,000 titles from over 5,000 international publishers, including coverage of 16,500 peer-reviewed journals in the scientific, technical, medical,...
database. He has also initiated
the study of protein domain dynamics by neutron spin echo
Neutron spin echo
Neutron spin echo spectroscopy is an inelastic neutron scattering technique invented by Ferenc Mezei in the 1970's, and developed in collaboration with John Hayter.In recognition of his work and in other areas, Mezei was awarded the first in 1999....
spectroscopy, providing a way to observe protein nanomachines in motion.
Previous work includes the invention of the microcanonical ensemble
Microcanonical ensemble
In statistical physics, the microcanonical ensemble is a theoretical tool used to describe the thermodynamic properties of an isolated system. In such a system, the possible macrostates of the system all have the same energy and the probability for the system to be in any given microstate is the same...
approach to lattice gauge theory
Lattice gauge theory
In physics, lattice gauge theory is the study of gauge theories on a spacetime that has been discretized into a lattice. Gauge theories are important in particle physics, and include the prevailing theories of elementary particles: quantum electrodynamics, quantum chromodynamics and the Standard...
with Aneesur Rahman
Aneesur Rahman
Aneesur Rahman pioneered the application of computational methods to physical systems. His 1964 paperon liquid argon studied a system of 864 argon atoms on a CDC 3600 computer, utilizing a Lennard-Jones potential. His algorithms still form the basis for many codes written today...
, cited over 100 times, work on the convexity of the effective potential of quantum field theory
Quantum field theory
Quantum field theory provides a theoretical framework for constructing quantum mechanical models of systems classically parametrized by an infinite number of dynamical degrees of freedom, that is, fields and many-body systems. It is the natural and quantitative language of particle physics and...
, and work on Langevin dynamics
Langevin dynamics
In physics, Langevin dynamics is an approach to the mathematical modeling of the dynamics of molecular systems, originally developed by the French physicist Paul Langevin...
in quantum field theory with John R. Klauder
John R. Klauder
John R. Klauder is an American professor of physics and mathematics and author of over 250 published articles on physics....
.
A monograph
discussing Quantum triviality
Quantum triviality
In a quantum field theory, charge screening can restrict the value of the observable "renormalized" charge of a classical theory. Ifthe only allowed value of the renormalized charge is zero, the theory is said to be "trivial" or noninteracting...
and whether an elementary scalar Higgs boson
Higgs boson
The Higgs boson is a hypothetical massive elementary particle that is predicted to exist by the Standard Model of particle physics. Its existence is postulated as a means of resolving inconsistencies in the Standard Model...
can exist was cited over 123 times in the HEP database. Another paper of his providing constraints on the Higgs boson has been cited over 103 times in that database as well. He has also published well-cited papers on topics including black holes, superconductors and protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
chemistry.
Callaway is an avid expedition mountaineer and polar explorer.
External links
- web page at NYU
- Dr. Callaway's publications on the SPIRES HEP Literature Database http://www.slac.stanford.edu/spires/find/hep/wwwcite?rawcmd=fin+a+callaway,d.
and on the PubMed database