Cyclin-dependent kinase 6
Encyclopedia
Cell division protein kinase 6 is an enzyme
that in humans is encoded by the CDK6 gene
.
It is regulated by Cyclin D
.
with CDKN2C
, P16
, PPM1B
, Cyclin D3, Cyclin D1
and PPP2CA
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the CDK6 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
It is regulated by Cyclin D
Cyclin D
Cyclin D is a member of the cyclin protein family that is involved in regulating cell cycle progression. The synthesis of cyclin D is initiated during G1 and drives the G1/S phase transition...
.
Interactions
Cyclin-dependent kinase 6 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with CDKN2C
CDKN2C
Cyclin-dependent kinase 4 inhibitor C is an enzyme that in humans is encoded by the CDKN2C gene.-Interactions:CDKN2C has been shown to interact with Cyclin-dependent kinase 4 and Cyclin-dependent kinase 6.-Further reading:...
, P16
P16 (gene)
Cyclin-dependent kinase inhibitor 2A, also known as multiple tumor suppressor 1 , is a tumor suppressor protein, that in humans is encoded by the CDKN2A gene...
, PPM1B
PPM1B
Protein phosphatase 1B is an enzyme that in humans is encoded by the PPM1B gene.-Interactions:PPM1B has been shown to interact with IKBKG, IKK2, Cyclin-dependent kinase 2, Cyclin-dependent kinase 6, CHUK and MAP3K7.-Further reading:...
, Cyclin D3, Cyclin D1
Cyclin D1
G1/S-specific cyclin-D1 is a protein that in humans is encoded by the CCND1 gene.Immunohistochemical staining of cyclin D1 antibodies is used to diagnose mantle cell lymphoma.-Interactions:...
and PPP2CA
PPP2CA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform is an enzyme that in humans is encoded by the PPP2CA gene.-Interactions:...
.